Dheivalakshmi, K (2021) Ethanolic Extract of Crotalaria Pallida Leaf against Scopolamine Induced Memory Impairment in Rat. Masters thesis, Annai J.K.K. Sampoorani Ammal College of Pharmacy, Komarapalayam.
Full text not available from this repository.Abstract
There has been a growing interest in the alternative medicine and the therapeutic properties of the natural products derived from plants in the recent years. Crotalaria pallida Aiton (Family: Fabaceae) leaves based on its traditional uses in the treatment of urinary disorders, external application as a poultice to treat painful swelling of joints and to reduce fever also reported Anti-inflammatory, antioxidant and anticholinesterase. As far as with above data the present work was carried out to study the memory enhancing activity of Crotalaria pallida Aiton. It is concluded that memory enhancing and anti-alzheimer’s effect of Crotalaria pallida might be due to the presence of anticholinesterase activity and phenolic compounds and flavonoids. Anti-inflammatory, antioxidant and anticholinesterase properties of Crotalaria pallida may be contributing favorably to the memory enhancement effect. Since scopolamine amnesia was reversed by Crotalaria pallida, it is possible that the beneficial effect on learning and memory was due to facilitation of cholinergic-transmission in mouse brain by inhibition of cholinesterase enzyme. However, further studies are necessitated to identify the exact mechanism of action. In the present investigation, Crotalaria pallida has shown promise as a memory enhancing agent in all the laboratory models employed. This study and its effective results may help them for find out a new active compound against adverse conditions of AD. Further phytochemical and pharmacological studies has to be progressed to elucidate in detail the active principle and real mechanism of action of this Ethanol extract of Crotalaria pallida.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 261925706 |
| Uncontrolled Keywords: | Ethanolic Extract, Crotalaria Pallida Leaf, Scopolamine Induced Memory Impairment, Rat. |
| Subjects: | PHARMACY > Pharmacology |
| Depositing User: | Ramakrishnan J |
| Date Deposited: | 04 Dec 2021 06:16 |
| Last Modified: | 28 Aug 2022 08:13 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/18860 |
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