Pratap Chander Ponraj, R (2021) Comparison of Facial Emotion Recognition Deficits among Treatment Responsive and Treatment Resistant subjects with Schizophrenia: A Case Control Study. Masters thesis, PSG Institute of Medical Sciences and Research, Coimbatore.
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Abstract
BACKGROUND: Though emotion recognition deficits had been consistently demonstrated in subjects with schizophrenia, most of the studies which showed emotion recognition deficits, had been done on first episode or chronic stable schizophrenia subjects, where they had grouped both treatment responsive & treatment resistant subjects without a priori definition of treatment resistance. Considering the evolving literature that treatment resistance could be a separate phenotypic subtype, cognitive deficits and social functioning needs to be systematically studied in a larger sample with a priori definition of treatment resistance. AIM: To compare the Facial Emotion Recognition among patients with Schizophrenia who are treatment responsive and treatment resistant, in comparison with healthy controls; to compare the social functioning across the various groups and to find association if any, between facial emotion recognition and social functioning in patients with schizophrenia. METHODS: 3-arm cross sectional study with chronic stable, treatment responsive and resistant schizophrenia (DSM-5), matched with healthy controls. Assessment done through a single 90min interview using scales including SANS, SAPS, SUMD, MARS, GSDS-2, CAI, CGI-Cogs, GAF and CGI. RESULTS: No statistically significant differences was noted among the two schizophrenia groups in terms of accuracy and over-identification. Global social functioning and multiple individual domains were more impaired in subjects with schizophrenia when compared to healthy controls. Similarly subjects with treatment resistant schizophrenia showed more impairment in global and individual domains of functioning when compared to subjects with treatment resistant schizophrenia. Global functional impairment in subjects with treatment resistant schizophrenia had significant association with higher over-identification scores. CONCLUSION: Facial Emotion Recognition Deficits seems to exist in Schizophrenia; but no major differences was noted in this area between treatment resistant and treatment responsive subjects with schizophrenia. Among subjects with treatment resistant schizophrenia, social functioning seems to be comparitively deficient, however comparitive studies with larger sample size and a more elaborate and objective assessment will help to get a better understanding about social functioning differences among treatment resistant and treatment responsive subjects.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 201828302 |
| Uncontrolled Keywords: | schizophrenia, resistance, responsive, social, cognition, functioning, facial, emotion, recogniton, correlation |
| Subjects: | MEDICAL > Psychiatry |
| Depositing User: | Subramani R |
| Date Deposited: | 02 Dec 2021 16:52 |
| Last Modified: | 09 Jan 2022 16:39 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/18744 |
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