Hariraj, V (2021) Assessment of Maternal Serum Docosahexaenoic Acid levels in Pre-Eclampsia and Uncomplicated Pregnancies. Masters thesis, Government Mohan Kumaramangalam Medical College, Salem.
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Abstract
OBJECTIVE: To assess the maternal Serum Docosahexaenoic acid levels in pre-eclampsia and uncomplicated pregnancies. MATERIALS AND METHODS: A case control study was conducted at Govt. Mohan Kumaramangalam Medical College and Hospital, Salem, a tertiary care hospital in Tamil Nadu during December 2018 – November 2019. The pregnant women who had been diagnosed with preeclampsia according to American College of Obstetricians and Gynecologists guidelines were identified and their medical records were reviewed. Various biochemical parameters including DHA, Uric acid, total protein, Hemoglobin were examined and compared between preeclamptic and normal pregnant mothers. RESULTS: A total of 40 preeclamptic mothers (between 32 to 36 weeks of gestation) as cases and 40 normotensive mothers as controls were included in this study. The mean DHA level of preeclamptic group was 271.93pg/ml and that of normal pregnant mothers were 515.36pg/ml. The mean difference between two groups were 243.43pg/ml and the p value was statistically significant. The mean creatinine level of preeclamptic group was 1.75mg/dl and that of normal pregnant mothers were 0.84mg/dl. The mean difference between two groups were 0.91mg/dl and the p value was statistically significant. The mean uric acid level of preeclamptic group was 6.33mg/dl and that of normal pregnant mothers was 3.83mg/dl. The mean difference between two groups was 2.50mg/dl and the p value was statistically significant. The mean serum protein levels of preeclamptic group was 5.20g/dl and that of normal pregnant mothers were 7.40g/dl. The mean difference between two groups were 2.2g/dl and the p value was statistically significant. Other parameters including blood sugar, blood urea, serum total cholesterol, serum triglycerides, serum HDL, platelet count, hemoglobin were compared between the two groups and found to be not statistically significant. CONCLUSION: The serum DHA levels were found to be low in preeclamptic mothers when compared with normotensive mothers.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 201823602 |
| Uncontrolled Keywords: | Maternal Serum Docosahexaenoic Acid levels, Pre-Eclampsia, Uncomplicated Pregnancies. |
| Subjects: | MEDICAL > Biochemistry |
| Depositing User: | Subramani R |
| Date Deposited: | 02 Dec 2021 16:43 |
| Last Modified: | 08 Jan 2022 12:14 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/18723 |
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