Fetal Cord Blood Sampling in Meconium Stained Liquor

Anitha Roselyn, P (2021) Fetal Cord Blood Sampling in Meconium Stained Liquor. Masters thesis, Coimbatore Medical College, Coimbatore.

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Abstract

INTRODUCTION: Meconium stained liquor was a commonly occuring phenomenon in day-to-day practice of obstetrics and its significance as a sign of fetal distress is controversial. Various authors has described the passage of meconium in utero to different mechanisms. With the decline of maternal mortality and morbidity over the few past decades modern obstetricians are much more concerned about the welfare of the fetus during pregnancy, labour and afterbirth. Presence of meconium in the fetus indicates fetal distress which causes severe birth asphyxia with the consequences such as brain damage, neurological problem and other manifestation. Hence the present study of “Fetal cord blood sampling in Meconium Stained Liquor” has been under taken to note the frequency of meconium staining of AF in obstetrical practice, to whether all meconium stained cases result in asphyxiated birth, to whether the amount of meconium discharge into the AF has any relation with fetal outcome, and the significance of cord blood gas analysis in determination of adverse fetal outcomes. AIMS AND OBJECTIVES: 1. To determine the relationship and predictive value of umbilical cord artery blood pH in relation to deliveries associated with meconium stained liquor. 2. To study the perinatal mortality and morbidity of neonates born with meconium stained amniotic fluid. 3. To determine the effect of thick and thin meconium on perinatal outcomes. MATERIALS AND METHODOLOGY: The study was undertaken at Government Coimbatore Medical College & Hospital in Coimbatore District, in the department of Obstetrics and Gynaecology, from January 2019- December 2019, During the study period, 100 samples were selected randomly from mother in labour with MSAF who were admitted for confinement in the said department. Results obtained were analysed by using SYSTAT package, RESULTS: APGAR score at birth was considered in the newborns. The distribution was, 2% were in 4/10, 16% in 5/10, 23% in 6/10. The rest had scores above 7, indicating the absence of fetal distress. While interpreting the cord blood gas analysis parameters, 30% had pH value within normal range, where 70% were in acidotic range. Out of the total 59 newborns who had apgar score more than 7, 37 were found to have respiratory acidosis, as analysed by cord blood gas analysis. Out of the total 14 who had normal pH values, 12 had apgar more than 7, and 2 had less than 7. CONCLUSION: Whatever is the staining of amniotic fluid, thick or thin, there is no difference in the mode of delivery, newborn admissions or occurrence of acidosis. In other words, thick or thin meconium staining hasn’t affected the perinatal morbidity. Even the newborns with APGAR score more than 7 had acidosis on blood gas analysis, which hasn’t manifested. A delay in decision for imminent delivery would affect the perinatal outcomes of these newborns in an adverse way.

Item Type: Thesis (Masters)
Additional Information: 221816301
Uncontrolled Keywords: Fetal Cord Blood Sampling, Meconium Stained Liquor.
Subjects: MEDICAL > Obstetrics and Gynaecology
Depositing User: Subramani R
Date Deposited: 03 Oct 2021 14:56
Last Modified: 03 Oct 2021 14:56
URI: http://repository-tnmgrmu.ac.in/id/eprint/18470

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