Akila, K (2016) Randomized double blind comparison of ketamine – propofol and fentanyl – propofol for the insertion of laryngeal mask airway in children. Masters thesis, Madras Medical College, Chennai.
|
Text
2010001akilak.pdf Download (8MB) | Preview |
Abstract
The ideal combination that provides smooth insertion conditions with minimal side effects has not been identified, particularly in children. In this study, 70 children of age 3-12 years are divided randomly into 2 groups: Group 1-Group-F-Fentanyl (n=35) received Fentanyl 2μg/kg and Group 2-Group –K- Ketamine (n=35) received Ketamine 0.5mg/kg before induction of anaesthesia..Baseline heart rate and arterial blood pressure were measured. Vital parameters (Heart rate and Arterial Blood Pressure) were measured before induction, before LMA insertion and thereafter at 1, 3 and 5 minutes after LMA insertion. Ideal LMA insertion conditions were evaluated with six variables by blinded observer: mouth opening, gagging, .head and limb movements, laryngospasm and resistance to insertion. Also the apnoea time was noted. RESULTS: The incidence of head/limb movements was statistically significant and Group Propofol – Ketamine showed 22% compared to Fentanyl-Propofol group (2.8%) Coughing/gagging was seen in 2.86% of both the groups. Resistance to insertion was statistically significant with p value of 0.0268 showing more in Propofol + Ketamine. There was no statistical significance in the occurrence of restricted mouth opening, restriction to LMA insertion and occurrence of swallowing between the two groups. Laryngospasm was absent in either groups. Fentanyl group showed the incidence of more apnoea (34.28) compared to Ketamine group (14.2).The heart rate (HR ),systolic blood pressure(SBP), diastolic blood pressure(DBP) and mean arterial pressure(MAP) were statistically more with Ketamine group than Fentanyl group. CONCLUSION: Co-induction with Fentanyl (2μ/kg) prior to Propofol (2.5mg/kg) induction for insertion of Laryngeal Mask Airway in children provided better insertion condition with minimal increase in heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure than admixture of Ketamine (0.5mg/kg) with Propofol .
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Double Blind; Ketamine – Propofol; Fentanyl – Propofol; Laryngeal Mask Airway in children |
| Subjects: | MEDICAL > Anaesthesiology |
| Depositing User: | Punitha K |
| Date Deposited: | 17 Jul 2017 12:06 |
| Last Modified: | 10 Aug 2017 01:49 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/1835 |
Actions (login required)
 |
View Item |
