Sriram Choudary, N (2016) The Efficacy of Systemic Enzyme Therapy for Edema Control in Mandibular Third Molar Impaction Surgery. Masters thesis, Ragas Dental College and Hospital, Chennai.
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Abstract
PURPOSE: The purpose of this prospective study was to determine the efficacy of systemic enzyme therapy for edema, mouth opening, and pain control in impacted mandibular third molar surgery. MATERIALS AND METHODS: 42 mandibular 3rd molar impactions assigned to the study (14 for each group – A, B, C). Systemic enzyme therapy administered postoperatively and compared between study groups A (Disperzyme) & B (phlogam) and control group C on 1st, 3rd, 5th postoperative days for changes in facial swelling, mouth opening and visual analog scale as parameters and analysed statistically. RESULTS: FACIAL SWELLING ASSESSMENT: The Disperzyme group exhibited an increase in facial swelling by 11% on day 1, gradually the swelling reduced to 7% on day 3 , on day 5 still a 3% increase in facial swelling from actual measurements were noted, there by the study group reduced 8% of total increase in swelling from post-operative day 1. The Phlogam group exhibited an increase in facial swelling by 11% on day 1, gradually the swelling reduced to 7% on day 3, on day 5 still a 3% increase in facial swelling from actual measurements were noted, there by the study group reduced 8% of total increase in swelling from post-operative day 1. The control group exhibited an increase in facial swelling by 15% on day 1, gradually the swelling reduced to 9% on day 3, on day 5 still a 7% increase in facial swelling from actual measurements were noted, there by the Control group reduced 8% of total increase in swelling from post-operative day 1. MAXIMUM MOUTH OPENING ASSESSMENT: The disperzyme group exhibited a mean mouth opening of 57% (31.43mm) on day 1, increasing to 69% (37.93mm) on day 3, reaching a maximum mouth opening of 78% (42.43mm) on day 5. The Phlogam group exhibited a mean mouth opening of 58% (29.29mm) on day 1, increasing to 68% (34.36mm) on day 3, reaching a maximum mouth opening of 79% (39.86mm) on day 5. The Control group exhibited a mean mouth opening of 40% (20.86mm) on day 1, increasing to 49% (25.14mm) on day 3, reaching a maximum mouth opening of 55% (28.21mm) on day 5. VISUAL ANALOG SCALE (PAIN ASSESSMENT):In Disperzyme group, patients reported with moderate pain in postoperative day 1 with mean value of 4 on VAS, which gradually reduced to mean value VAS score of 1 on day 3 which remained to be at VAS score of 1 till day 5. In Phlogam group, patients reported with moderate pain in postoperative day 1 with mean value of 5 on VAS, which gradually reduced to mean value VAS score of 3 on day 3 & remained to be at VAS score of 1 till day 5. In Control group, patients reported only mild pain in post-operative day 1 with mean value of 3 on VAS, which gradually reduced to mean value VAS score of 1 on day 3 which remained to be at VAS score of 1 till day 5. CONCLUSION: The control group had statistically significant residual edema of 4% when compared with study groups, concluding that SYSTEMIC ENZYME THERAPY (SET) is comparatively efficient in reducing edema than NSAID’s. The study groups have shown significant statistical difference with improved mouth opening by 23.5% (12.93mm) when compared with control group, concluding that systemic enzyme therapy (SET) is comparatively efficient for mouth opening than NSAID’s. Subjective assessment of pain using visual analog scale revealed mean score of 4.5 (moderate pain) for both study groups , while control group mean score of VAS was 1 (mild pain) on follow-ups, Concluding that control group - NSAID’S was better in reducing pain than the study groups.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Mandibular third molar surgery, complications of mandibular third molar surgery, methods for edema control, routes of drug administration, role of NSAID’S, steroids, and systemic enzyme therapy. |
| Subjects: | DENTAL > Oral and Maxillofacial Surgery |
| Depositing User: | Subramani R |
| Date Deposited: | 21 Sep 2021 03:39 |
| Last Modified: | 21 Sep 2021 03:39 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/18057 |
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