Dermatoglyphic patterns as predictors of treatment response in Schizophrenia.

Aastha, - (2006) Dermatoglyphic patterns as predictors of treatment response in Schizophrenia. Masters thesis, Christian Medical College, Vellore.


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Dermatoglyphics (from ancient Greek derma = "skin", glyphe = "carve") is the scientific study of fingerprints. The term was coined by Cummins and Midlo in 1926. In humans, dermatoglyphics is present on fingers, palms, toes, and soles, and give insight into a critical period of embryogenesis, between 4 weeks and 5 months, when the architecture of the major organ systems is developing. Dermatoglyphics has been studied for fortune telling by palmists and as a definitive and unalterable tool for identification by forensic experts. Widespread medical interest in epidermal ridges developed only in the last few decades when it became apparent that many patients with chromosomal aberrations had unusual ridge patterns. Inspection of skin ridges therefore promised to provide a simple, inexpensive means of information to determine whether a given patient could have a particular chromosomal defect. OBJECTIVES: To Identify, 1. Whether abnormal neurodevelopmental markers manifest more in treatment resistant schizophrenia, than in treatment responders by studying dermatoglyphic markers. 2. Whether treatment resistance can be predicted by examining dermatoglyphic variables. METHODS: Data are expressed as number (%) and mean +/- standard deviation for categorical and continuous variables. Chi-square/Fisher’s exact tests were used for group comparisons. Independent t- test (for normal data) and Mann-Whitney test (for non-normal data) were performed to compare the mean scores between treatment responders and non- responders. Pearson correlation analysis were done to assess the relationship between treatment responders and non- responders with respect to the ridge counts. All the analysis were carried out using SPSS software Vs. 11.0. RESULTS: There was increased pattern frequency in the I3 area of the left hand of non-responders and in the I4 area of the right hand of responders. atd angle was decreased in the left hand of non-responders. There was increased frequency of the Simian type I crease in male non-responders and Sydney line in female nonresponders. The t’ position of axial triradius is the most common position in male non-responders. There is no significant correlation in the ridge counts of second and fourth digits of female non-responders and in a-b ridge counts in nonresponders.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Dermatoglyphic patterns; predictors of treatment; schizophrenia.
Subjects: MEDICAL > Anatomy
Depositing User: Kambaraman B
Date Deposited: 22 Jun 2017 05:18
Last Modified: 05 Feb 2018 02:39

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