A Study of Obstetric Outcome After Previous Spontaneous Abortion in First Trimester

Malathy, G S (2022) A Study of Obstetric Outcome After Previous Spontaneous Abortion in First Trimester. Masters thesis, Thoothukudi Government Medical College, Thoothukudi.

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Abstract

INTRODUCTION: The word ‘abortion’ derives from the Latin word ‘aboriri’ meaning ‘to miscarry’. Abortion is defined as spontaneous or induced termination of a pregnancy before viability of fetus. It is thus appropriate that miscarriage and abortion are terms used interchangeably in a medical context. But, because of popular use of the word ‘abortion’ by laypersons implies a intended termination of intact pregnancy, but still, many prefer the word ‘miscarriage’ for spontaneous fetal loss than abortion. AIM OF THE STUDY: The major goal of my study is to calculate the risk of low birth weight, preterm delivery, intrauterine fetal death (IUD), intrauterine growth retardation (IUGR), stillbirth, premature rupture of membrane (PROM) in women with previous history of spontaneous abortions, and any other adverse outcomes in women with previous history of spontaneous abortions. OBJECTIVES: 1. To assess whether a previous unfavourable pregnancy outcome increases the chance of a negative pregnancy outcome in the current one. 1. To look for a link between the previous spontaneous abortion and preterm delivery, IUGR, low birth weight, PROM, stillbirth, or IUD in subsequent pregnancies. MATERIALS AND METHODS: Sample Size: 150 cases. Source of data: This prospective study was carried out in 150 pregnant women attending OPD and labour ward of O&G department in Government Thoothukudi Medical College and Hospital during the period for 2 years from November 2019 to November 2021. Inclusion criteria: In this study patients with history of spontaneous abortion, irrespective of cause and period of gestation were included. • Age group: 18 to 35 years. • Patients with one and/or more than one spontaneous abortion. • Patients with previous live birth, followed by spontaneous abortion. Exclusion criteria: • Patients with induced abortion. • History of spontaneous abortion with twin gestation. • History of PIH, chronic hypertension, GDM, juvenile DM, heart disease, anaemia. • History of carcinoma. • History of HIV/HBsAG/VDRL infections. SUMMARY: • Previous unfavourable pregnancy outcome increases the risk of adverse outcome in the future pregnancies. • There is association between previous spontaneous abortion and increased risk of preterm delivery (7.33%), PROM (15.33%), and low birth weight (14.67%) in the subsequent pregnancies. • There is no statistically significant increase in the rate of IUGR, stillbirth and IUD in the subsequent pregnancies. • As the number of previous abortions increase the incidence of successful outcome decreases. A striking feature of this study is that the incidence of PROM (15.33%), and preterm (7.33%) were significantly higher in women who had history of previous one abortion. • As the number of previous abortions increase the incidence of low birth weight (14.67%) increases. CONCLUSION: Miscarriage is the most common complication of pregnancy. There is no currently definitive predictive test or treatment currently available that can prevent spontaneous miscarriage. About 50% of miscarriage is associated with chromosomal anamolies. Remaining cases are likely to be euploid fetuses that have failed due to implantation problem. Patients with previous history of spontaneous abortion are associated with adverse pregnancy outcome in their future pregnancy. The complication and fetal loss can be reduced by early booking of the patient and giving good antenatal care. It has been established that supportive care and frequent antenatal check-up and scan will improve the pregnancy outcome. Women with previous history of miscarriage should be reassured and sonography should be done at the earliest for next pregnancy.

Item Type: Thesis (Masters)
Additional Information: 221916802
Uncontrolled Keywords: Obstetric Outcome, after Previous Spontaneous Abortion, First Trimester.
Subjects: MEDICAL > Obstetrics and Gynaecology
> MEDICAL > Obstetrics and Gynaecology
Depositing User: Subramani R
Date Deposited: 21 May 2021 14:49
Last Modified: 10 Dec 2023 10:32
URI: http://repository-tnmgrmu.ac.in/id/eprint/17250

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