Preparation and Evaluation of Buccal Patch of Hydrocortisone Sodium Succinate for Local.

Preetha, Francis (2013) Preparation and Evaluation of Buccal Patch of Hydrocortisone Sodium Succinate for Local. Masters thesis, Ultra College of Pharmacy, Madurai, Tamil Nadu, India.

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The study shows the anti inflammatory action loaded in the patches which will be reducing the paining of the mouth in adults which compared in different water soluble mucoadhesive polymers. The mucosal layer lines a number of regions of the body including the gastrointestinal tract, buccal cavity, airways, ear, nose, eye, urogenital tract, vagina and rectum are covered with a thick gel like structure known as mucin, therefore all bioadhesives must interact with the mucin layer during the process of attachment, these represent the potential sites for attachment of any bioadhesive system Buccal tablets , lozenges and pastes are used in relieving pain, inflammation associated with oral mucosal diseases like inflammations, oral submucous fibrosis, ulcer, and other lesions. Hydrocortisone sodium succinate is used as an anti inflammatory agent. The most important advantage of the mucoadhesive buccal films is that it contains a lower drug dose, adequate for therapeutic effect as it is placed directly on the site of the inflammation, when compared to conventional administration. Moreover, mucoadhesive buccal patches are convenient and comfortable to use as they are non-irritant and self administration is possible.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Buccal Patch; Hydrocortisone; Sodium Succinate; Local
Subjects: PHARMACY > Pharmaceutics
Depositing User: Ravindran C
Date Deposited: 14 Jul 2017 07:08
Last Modified: 14 Jul 2017 07:08

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