Formulation and Evaluation of Lornoxicam Niosomal Topical Gel

Palanivel, V (2012) Formulation and Evaluation of Lornoxicam Niosomal Topical Gel. Masters thesis, College of Pharmacy, Madurai Medical College, Madurai.

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A chronic illness has been mostly accomplished by delivery of drugs to patients using various pharmaceutical conventional dosage forms (such as tablets, capsules, pills, suppositories, creams, ointments, liquids, aerosols and injectables as drug carriers) (Chien Yie.W, 2005). Even today conventional drug delivery system occupies most of the part in a prescription as well as drug store. This type of drug delivery system is known to provide a prompt release of drug. Therefore, to achieve as well as to maintain the drug concentration within the therapeutically effective range needed for treatment, it is often necessary to take this type of drug delivery system several times a day (Chien Yie.W, 2005). study it is concluded that the niosomes can be considered as promising drug delivery vehicles which increase the duration of the drugs. Thus niosomes help in formulating dosage forms having more prolonged action. The niosomal delivery of lornoxicam in carbopol gel base acts as a suitable topical drug delivery system which may be given safely to all patients suffering from rheumatoid arthritis and osteoarthritis. The stability of niosomes improved after incorporation into gel base may be due to prevention of fusion of niosomes. Further the pharmacokinetic and other clinical studies may be carried out in future.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Lornoxicam ; Niosomal ; Topical Gel.
Subjects: PHARMACY > Pharmaceutics
Depositing User: Ravindran C
Date Deposited: 14 Jul 2017 07:00
Last Modified: 22 Dec 2018 09:06

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