A Cross Sectional study on the Prevalence of Comorbidities among the SARS-COV-2 Deaths Reported in Tertiary Care Centre

Nivedhan, M (2023) A Cross Sectional study on the Prevalence of Comorbidities among the SARS-COV-2 Deaths Reported in Tertiary Care Centre. Masters thesis, Thanjavur Medical College, Thanjavur.

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Abstract

INTRODUCTION: The strength and power of a disease is always determined by its case fatality rate. The new SARS-COV-2 pandemic have been made significant panic with its mortality among subjects with underlying health conditions and age extremes. OBJECTIVES: The study was done with an objective to assess the impact of Covid-19 infection on the most frequent comorbidities encountered amongst those who have died due to this pathogen. The study also wanted to identify the high-risk group in this pandemic and prioritising them for vaccination. And also, to estimate the most prevalent comorbidity in the study population. METHODOLOGY: The study was done as a retrospective observational study among subjects who deceased due to Covid-19 in a particular period. The study was done among 796 deceased subjects who were selected consecutively from deaths reported due to Covid-19 between June 2020 and June 2021 as reported by the Ministry of Health. Deaths with confirmed RT-PCR positive result for SARS-COV-2 and patients with age >15 years were included in the study. Patients who recovered from SARS-COV-2 infection and reactive patients who were discharged and later expired due to other causes were excluded from the study. The available data generally included information about the age, gender, confirmed positive, the date of death and their underlying comorbidities. The data was entered into Microsoft excel and analysed using SPSS 23. RESULTS: The mean (SD) of age in years among the population was 60.35 (13.41) years. In the study 554 (69.6%) subjects who deceased due to Covid-19 were males and 242 (30.4%) were females. Among the deceased Covid-19 patients showed that 616 (77.4%) subjects had presence of co-morbidities. The Frequency distribution of type of comorbidity observed in the deceased Covid-19 patients showed that Diabetes mellitus (DM) was present for 431 (70%), Systemic hypertension (SHT) 334 (54.2%), Coronary artery disease (CAD) 124 (20.1%) and Chronic kidney disease (CKD) 93(15.1%).I n the study subjects presence of comorbidity was significantly older than those without comorbidity [61.58 (11.93) vs. 56.15 (16.91)] The comorbid status with respect to age shows that majority of comorbidity were present in the age group of 61-80 years 303(49.2%) and 41-60 years (259 (42%)). The correlation between time spent in hospital before death with age, number of days of symptoms before admission, duration and number of comorbidities and comorbidity status were not significantly different. CONCLUSION: The study showed that male gender, older subjects were mostly deceased among the population. The study showed diabetes and hypertension to be the most prevalent comorbidities and no significant difference in duration of hospital stay with the presence of comorbidities.

Item Type: Thesis (Masters)
Additional Information: 200120102508
Uncontrolled Keywords: Covid-19, SARS COV-2, Comorbidities, Prevalence.
Subjects: MEDICAL > General Medicine
> MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 15 May 2021 13:08
Last Modified: 24 Mar 2024 02:27
URI: http://repository-tnmgrmu.ac.in/id/eprint/16781

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