Agollu, Monisha (2013) Formulation and Evaluation of Methylphenidate Hydrochloride Extended Release Capsules. Masters thesis, C L Baid Metha College of Pharmacy, Chennai.
|
Text
Agollu Monisha.pdf Download (2MB) | Preview |
Abstract
The treatment of acute diseases or chronic illness was achieved by delivery of drugs to patients from many years. These drug delivery systems include tablets, injectables, capsules, suspensions, creams, ointments, liquids and aerosols. Nowadays these drug delivery systems are widely used. The term drug delivery system can be defined as techniques which are used for getting therapeutic agents inside the human body. The formulation containing 40mg of Methylphenidate Hydrochloride was prepared as extended release capsules.These techniques are particularly useful for patients who should not administer the drug in repeated intervals. The optimized formulation have consistent release profile to provide the drug release for longer duration of 10 hours. FTIR studies have shown that there was no considerable interactions between drug and excipients.The short term stability study also indicates no change in the physical characteristic of drug content. The comparision of dissolution profiles between the Methylphenidate Hydrochloride extended release capsules 40mg and the reference drug, showed no major changes in the dissolution profiles. Hence, it can be concluded that the Methylphenidate Hydrochloride extended release capsules were successfully developed and evaluated.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Formulation ; Evaluation ; Methylphenidate ; Hydrochloride ; Extended Release Capsules. |
| Subjects: | PHARMACY > Pharmaceutics |
| Depositing User: | Ravindran C |
| Date Deposited: | 14 Jul 2017 05:59 |
| Last Modified: | 15 May 2018 23:25 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/1677 |
Actions (login required)
 |
View Item |
