Dharini, M (2022) Comparative study of Cervical Ripening with Sublingual Misoprostol Vs Intracervical Dinoprostone Gel in term Prelabour Rupture of Membranes. Masters thesis, Thanjavur Medical College, Thanjavur.
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Abstract
● The maximum age group in the study was between 26-30 years, with significant difference between the groups. ● The Bishop score was little bit favourable in the dinoprostone group before induction of labour. ● The improvement in Bishop score was more with group A (misoprostol sublingually) than group B (those with dinoprostone gel) and was statistically significant with p values 0.00 and 0.001 at zero and at 4 hours. ● Induction to delivery interval was shorter in sublingual Misoprostol group when compared to the dinoprostone gel applied intracervical. ● Most of the participants delivered by normal vaginal delivery in both the groups. ● When compared maximum number of LSCS was observed in misoprostol group. ● The complication observed i.e. Meconium stained amniotic fluid was more in Misoprostol group. ● Fetal distress was more in misoprostol group. ● APGAR <7 and babies requiring NICU admission was more in Misoprostol group. ● GI effects was observed more in dinoprostone gel group when compared to misoprostol group. ● Postpartum Haemorrhage was more in the misoprostol group CONCLUSION: From this study it has been observed that though there is no major difference between the group induced with misoprostol by sublingual route or in the group induced with Intracervical application of dinoprostone gel, the induction time is less in the group administered with sublingual misoprostol than dinoprostone and misoprostol given sublingually is having higher maternal febrile morbidity, higher rates of meconium stained amniotic fluid, fetal distress and NICU admission than intracervical dinoprostone gel induction and hence dinoprostone has much more promising advantage over the other in terms of fetal outcome. Thus it was concluded that though sublingual misoprostol is efficacious than intracervical dinoprostone, its safety margin is very less and hence misoprostol induction should be done only in a double setup under medical supervision.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 220620102516 |
| Uncontrolled Keywords: | Cervical Ripening, Sublingual Misoprostol, Intracervical Dinoprostone Gel, Prelabour Rupture, Membranes. |
| Subjects: | MEDICAL > Obstetrics and Gynaecology > MEDICAL > Obstetrics and Gynaecology |
| Depositing User: | Subramani R |
| Date Deposited: | 15 May 2021 12:33 |
| Last Modified: | 03 Dec 2023 15:14 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/16703 |
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