Madhusudhanan, R (2021) Effect of Nalbuphine as Adjuvant to 0.5% Bupivacaine in Ultrasound Guided Supraclavicular Brachial Plexus Block. Masters thesis, Thanjavur Medical College, Thanjavur.
|
Text
201000521madhusudhanan.pdf Download (9MB) | Preview |
Abstract
BACKGROUND: Effect of Nalbuphine as adjuvant to 0.5% Bupivacaine in ultrasound guided supraclavicular brachial plexus block. MATERIALS AND METHODS: A Prospective randomised controlled study was conducted on 60 patients of ASA I and II of both genders aged between 18 and 60 years undergoing upper limb surgeries using nalbuphine as an adjuvant to 0.5 % bupivacaine for supraclavicular brachial plexus block with ultrasound guidance, with an aim to evaluate the effect of k- partial agonist nalbuphine.. The control group (Group C) received 0.5% bupivacaine (20ml) and 2 ml normal saline whereas nalbuphine group (group N) received 0.5% bupivacaine (20ml) and 20 mg (2ml) nalbuphine. Patients were observed for onset of sensory and motor block, duration of motor block and duration of analgesia as primary end points whereas blood pressure (systolic, diastolic and mean arterial pressure), heart rate and Sp02 were noted as secondary outcome. RESULTS: The onset of sensory (36%) and motor blockade (16%) were faster in nalbuphine group (P < 0.001). Duration of motor block was longer (33%) in nalbuphine group compared to control group(P < 0.001). Duration of analgesia (42%) was prolonged in nalbuphine group (P<0.001). Nalbuphine group patients were calm and quiet with stable hemodynamics. CONCLUSION: Nalbuphine (20mg) as an adjuvant to 0.5% bupivacaine in ultrasound guided supraclavicular brachial plexus block had faster onset of sensory and motor blockade, longer duration of motor blockade and analgesia. Nalbuphine is a safe, economical and better adjuvant in peripheral nerve blocks and also gives calm patients with stable hemodynamics.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 201820203 |
| Uncontrolled Keywords: | Nalbuphine, Bupivacaine, Ultrasound guided, Supraclavicular brachial plexus block. |
| Subjects: | MEDICAL > Anaesthesiology |
| Depositing User: | Subramani R |
| Date Deposited: | 13 May 2021 16:31 |
| Last Modified: | 08 Jan 2022 11:55 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/16686 |
Actions (login required)
 |
View Item |
