Nirmal Kumar, M (2021) A Comparative study of Dexmedetomidine and Magnesium Sulfate as Adjuvants with Ropivacaine for Spinal Anaesthesia in Infraumbilical Surgeries and Postoperative Analgesia. Masters thesis, Thanjavur Medical College, Thanjavur.
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Abstract
BACKGROUND: This study was designed to compare the efficacy of intrathecal dexmedetomidine and magnesium sulfate for onset & duration of sensory & motor block, duration of analgesia, post operative pain & to evaluate the side effects, if any. AIM OF THE STUDY: To compare anaesthetic and analgesic properties of intrathecal dexmedetomidine versus magnesium sulfate as adjuvants to 0.75% isobaric ropivacaine for infraumbilical surgeries. STUDY DESIGN: A prospective randomized double-blinded study. MATERIALS AND METHOD: After getting the Institutional Ethics Committee approval, this study was conducted on fifty patients of the American Society of Anesthesiologists physical Status I and II aged between 20 and 65 years of either sex and scheduled to undergo infraumbilical surgeries under spinal anesthesia. They were divided into two groups of 25 each. Group D patients received 3 ml of 0.75% isobaric ropivacaine hydrochloride with 10 μg of dexmedetomidine in 0.5ml normal saline, whereas Group M patients received 75 mg of MgSO4 in the place of dexmedetomidine. The quality of surgical analgesia and quality of intraoperative muscle relaxation were assessed and graded. RESULTS: We found out that onset of sensory and motor block was earlier in Group D in comparison to Group M. There was a significant reduction in the time to the first rescue analgesia in group receiving intrathecal dexmedetomidine. CONCLUSION: It is concluded from our study that ropivacaine plus dexmedetomidine group is better than ropivacaine plus MgSO4 in providing early onset of sensory and motor block as well as in providing postoperative analgesia.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 201820205 |
| Uncontrolled Keywords: | Dexmedetomidine, magnesium sulfate, ropivacaine, spinal anaesthesia, visual analog scale. |
| Subjects: | MEDICAL > Anaesthesiology |
| Depositing User: | Subramani R |
| Date Deposited: | 13 May 2021 16:30 |
| Last Modified: | 08 Jan 2022 12:01 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/16684 |
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