Sandeep, Suresh (2014) A study on incidence and clinical profile of fungal sinusitis in patients diagnosed with chronic rhinosinusitis. Masters thesis, PSG Institute of Medical Sciences & Research, Coimbatore.
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Abstract
Aim: To study the incidence and clinical profile of fungal sinusitis in diagnosed cases of chronic rhinosinusitis. Materials and Methods: This was a prospective study in which 100 patients with chronic rhinosinusitis who underwent treatment in the department of E.N.T at a tertiary care centre over two years were randomized into the study. Diagnosis was confirmed by fungal culture and pathological examination of the excised specimen. The data collected from the patients was analysed by Pearson Chi- Square and Fisher’s Exact tests. Patients underwent either endoscopic sinus surgery or medical line of management or a combination of both. Results: Fungal rhinosinusitis was more common in the elderly age groups with involvement of maxillary sinus in most of the cases. Nasal discharge, nasal obstruction and headache were the most common presenting symptoms. Pathological examination had a higher sensitivity than microbiology examination in the diagnosis. Mucor was the most commonly isolated organism. Fungal sinusitis was comparatively more common among immunocompetent individuals. More than one-third of cases were invasive fungal rhinosinusitis. Complications were more in cases of mucormycosis. Surgery with chemotherapy offered better treatment outcome as compared to single modality. Conclusion: Early detection and treatment of fungal rhinosinusitis is the key in tackling this clinical condition which can otherwise be fatal.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | chronic rhinosinusitis; fungal sinusitis; immunocompromised state; mucormycosis; aspergillus |
| Subjects: | MEDICAL > Otolaryngology |
| Depositing User: | Devi S |
| Date Deposited: | 13 Jul 2017 11:26 |
| Last Modified: | 13 Jul 2017 11:26 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/1665 |
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