To compare the dosimetry of three linear accelerator based Stereotactic Radiotherapy (SRT) techniques static conformal field (SCF), Static Conformal Arc (SCA) and Dynamic Conformal Arc (DCA) for pituitary adenoma and craniopharyngioma

Muttanagouda, Giriyapp goudar (2016) To compare the dosimetry of three linear accelerator based Stereotactic Radiotherapy (SRT) techniques static conformal field (SCF), Static Conformal Arc (SCA) and Dynamic Conformal Arc (DCA) for pituitary adenoma and craniopharyngioma. Masters thesis, Christian Medical College, Vellore.

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Abstract

To compare the dosimetric outcomes of the three linear accelerator based stereotactic radiotherapy techniques, Static Conformal Field (SCF), Static conformal Arc and Dynamic conformal arc (DCA), for the treatment of Pituitary adenoma and Craniopharyngioma. Materials and methods: Computer image sets of 20 patients who have been diagnosed either as Pituitary adenoma or Craniopharyngioma and treated with Stereotactic radiotherapy (SRT) were selected for the study. For each data set, three SRT plans, one each with SCF, SCA and DCA techniques were generated using Brain LAB, iPlan RT V.4.5.3, TPS software. The Conformity index (CI), Homogeneity index (HI), Quality of coverage of the target, Dose volume histograms for the target and organs at risk and the time taken to deliver treatment were compared across these three sets of plan. Results: There were 12 patients with Pituitary adenoma and eight patients with Craniopharyngioma. All patients had surgical excision of the tumour prior to radiotherapy. The conformity and homogeneity indices were comparable across three techniques. The quality of coverage was comparable in static conformal field and DCA techniques, where as it is slightly inferior in static conformal arc technique. The organs at risk are better spared in SCF and DCA techniques compared to SCA technique. The time taken to deliver treatment was lesser in SCF compared to SCA and DCA. Conclusions: The Conformity Index and Homogeneity Index were comparable across the three plans but Quality of target coverage was superior in DCA. Dynamic Conformal Arc (DCA) technique was the best technique among the three in achieving all the indices. Doses to normal organs, Optic Chiasm and Brain stem were better controlled in SCF technique than SCA and DCA technique.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Dosimetry of three-linear, Stereotactic Radiotherapy (SRT), Techniques Static Conformal Field (SCF), Static Conformal Arc (SCA), Dynamic Conformal Arc (DCA), Pituitary Adenoma and Craniopharyngioma
Subjects: MEDICAL > Radio Therapy
Depositing User: Punitha K
Date Deposited: 13 Jul 2017 10:40
Last Modified: 04 Jun 2021 01:54
URI: http://repository-tnmgrmu.ac.in/id/eprint/1651

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