A Cross Sectional study to Estimate the Incidence of Anaemia and Its Types among Chronic Liver Disease Patients Listed for Liver Transplantation in a Tertiary Care Centre in Chennai

Richard Raj, R (2021) A Cross Sectional study to Estimate the Incidence of Anaemia and Its Types among Chronic Liver Disease Patients Listed for Liver Transplantation in a Tertiary Care Centre in Chennai. Masters thesis, Stanley Medical College, Chennai.

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Abstract

INTRODUCTION: Fibrosis is a reversible scarring response that occurs in almost all patients with chronic liver injury. Hepatic fibrosis at last leads to cirrhosis, characterized by nodule formation and organ contraction. The causes of cirrhosis are numerous and include congenital, metabolic, inflammatory, and toxic liver diseases. OBJECTIVES: 1. To Estimate the Incidence of Anaemia among Chronic Liver Disease Patients listed for Liver Transplantation. 2. To Assess the various types of Anaemia among them. METHODOLOGY: Study Design: Cross Sectional study. Study Population: Chronic Liver Disease Patients Listed for Liver Transplantation. Sampling Method: Convenient Sampling. Place of Study: Department of Medical Gastroenterology and Department of Internal Medicine, Government Stanley Hospital, Chennai. Study Period: One Year. (September 2019-September 2020). Sample Size: 70. CONCLUSION: After assessing the various types of Anaemia among Chronic Liver Disease Patients Listed for Liver Transplantation, The Most Common Cause had been found to be Gastro Intestinal Hemorrhage Thereby causing Normocytic Normochromic Anaemia. Based on the “spectrum of anemia in liver disease patients “article published in the world journal of gastro enterology and comparing it with my studies, I come to a conclusion that the major risk factor causing chronic liver disease appears to be Alcoholism and among the various types of Anemia studied above, acute blood loss anemia due to gastro intestinal hemorrhage predominantly variceal is the most common type seen compared to others. Hence the normocytic normochromic type. As a result majority of the patients posted for liver transplantation as in my study have already undergone endoscopic variceal ligation at the time of acute decompensation and a few as a precautionary method. Periodic endoscopy to check the status of the banding is necessary to prevent future episodes of bleeding which can be detrimental to the patient who other than that would appear to be doing well having posted for transplantation.

Item Type: Thesis (Masters)
Additional Information: 201811069
Uncontrolled Keywords: Anaemia, Chronic Liver Disease Patients, Liver Transplantation, Tertiary Care Centre, Chennai.
Subjects: MEDICAL > General Medicine
Depositing User: Subramani R
Date Deposited: 04 May 2021 09:22
Last Modified: 25 Sep 2021 03:20
URI: http://repository-tnmgrmu.ac.in/id/eprint/15809

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