Malaria screening among Voluntary Blood Donors - to find out the prevalence - to evaluate the sensitivity of different techniques.

Latha, B (2013) Malaria screening among Voluntary Blood Donors - to find out the prevalence - to evaluate the sensitivity of different techniques. Masters thesis, The Tamil Nadu Dr. M.G.R. Medical University, Chennai.


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Voluntary Blood Donors constitute the safest source of blood ‘contribution’ to save the lives of thousands of people every day. In India, any healthy individual between the ages of 18 to 65 years can donate blood once in three months interval, maximum up to 188 times in their life time.1 Blood Transfusion Service is a vital part of the National Health Service and there is no substitute for human blood and its components. According to WHO, blood donation should be absolutely voluntary and free and the motive should be purely altruistic to help the unknown recipient. Blood Safety, therefore, remains an issue of major concern in transfusion medicine in developing countries where national blood transfusion services and policies, appropriate infrastructure, trained personnel and financial resources are lacking.2 The worldwide data for the global database for blood safety of the 162 countries 39 countries are not routinely testing blood donations for one or more of the four major TTIs. In our study, among 250 voluntary blood donors in a malarial endemic area one sample was found positive by microscopy, Quantitative Buffy Coat Method and Rapid Diagnostic Test. Since intermittent asymptomatic period, recrudescence and relapse are known with P.vivax infection in an endemic area, especially in semi-immune individuals, it is imperative to screen all donors by less-laborious, less time-consuming and more sensitive methods, irrespective of a strict donor questionnaire. RDT in our study was found equally sensitive to QBC and microscopy. QBC is more sensitive; however it needs specialized instruments, higher technical expertise and is costlier compared to RDT. Hence, to prevent transfusion transmitted malaria in endemic areas like India screening of malaria by RDT may be included along with microscopy. However, a study on large number of voluntary blood donors is necessary to arrive at a definitive conclusion.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Malaria screening ; Voluntary Blood Donors ; Sensitivity of different techniques.
Subjects: MEDICAL > Immunohaematology Blood Transfusion
Depositing User: Kambaraman B
Date Deposited: 21 Jun 2017 07:01
Last Modified: 16 Jun 2019 02:21

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