Meshach, J (2023) A Comparative study of the Prognostic Significance of Curb 65 and Expanded Curb 65 in Community Acquired Pneumonia Patients. Masters thesis, Kilpauk Medical College, Chennai.
|
Text
2001 004 23 Meshach J.pdf Download (2MB) | Preview |
Abstract
INTRODUCTION: Community acquired pneumonia is the eighth leading cause of mortality worldwide. Several scoring systems have been devised in the past to compute CAP severity. The aim of this study is to compare the prognostic significance of CURB 65 and Expanded CURB 65 in CAP patients. These are simple tests which can be done on day 1 of admission and have profound value in identifying the at risk individuals. AIM OF THE STUDY: The aim of the study is to compare the prognostic significance of CURB 65 and expanded CURB 65 in community acquired pneumonia patients. PRIMARY OBJECTIVES: 1. To assess the length of stay in hospital in CAP patients and their CURB 65 and expanded CURB 65 score at admission. 2. To assess the need for intensive medical care admission in CAP patients and their CURB 65 and expanded CURB 65 score at admission. 3. To assess the in hospital mortality rate in CAP patients and their CURB 65 and expanded CURB 65 score at admission. SECONDARY OBJECTIVE: 1. To correlate the serum LDH levels ,serum albumin levels and platelet levels with curb 65 and expanded curb 65 scoring. MATERIALS AND METHODS: The present study titled “A COMPARATIVE STUDY OF THE PROGNOSTIC SIGNIFICANCE OF CURB65 AND EXPANDED CURB65 IN COMMUNITY ACQUIRED PNEUMONIA PATIENTS” was carried out in the Department of General Medicine, Government Royapettah Hospital, Government Kilpauk Medical College Hospital, Chennai. 1. Study Design: Prospective cohort study. 2. Period of study: April 2022 to September 2022 3. Duration of study: 6 months. 4. Place of study: Government Royapettah Hospital, Chennai. 5. Study population: Inclusion criteria: 1. Age more than 18 years of both sex. 2. Patients with at least two clinical signs and symptoms related to pneumonia (fever, cough, chest pain, dyspnoea and crackles on auscultation). 3. New infiltrates on chest x ray. Exclusion criteria: 1. Age < 18 years, 2. Malabsorption and malnutrition status, 3. HIV infection, 4. Organ transplant recipient, 5. On immunosuppressant and steroids, 6. Pregnancy and lactation, 7. Symptoms after 48 hours of hospitalization. Sample size: 100 patients of community acquired pneumonia in Government Royapettah Hospital. RESULTS: In this study it was found that both scores predicted the length of hospital stay, need for intensive care, need for mechanical ventilation with equal significance. However expanded curb score is sensitive in predicting the mortality better than curb 65 since it includes platelets, albumin and serum LDH values. Further serum albumin on day one admission is a better predictor of longer duration of hospital stay and intensive care. CONCLUSION: In a resource limited setting, CURB 65 is not inferior to expanded curb 65 in identifying the at risk patients and serum albumin better predicts mortality. Expanded curb 65 is sensitive but not specific in assessing the mortality.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | Reg.No.200120102012 |
| Uncontrolled Keywords: | Prognostic Significance, Curb 65, Expanded Curb 65, Community Acquired Pneumonia Patients. |
| Subjects: | MEDICAL > General Medicine > MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 04 May 2021 09:06 |
| Last Modified: | 22 Mar 2024 16:15 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/15784 |
Actions (login required)
 |
View Item |
