Laviniya, N (2022) A Comparative Diagnostic Validity of Two Colposcopic Indices-Reids Index and Swede Score with Cervical Histology. Masters thesis, Stanley Medical College, Chennai.
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Abstract
Cervical cancer which was the second most common cancer worldwide. Since it has the larger preinvasive stage, it is very easy to screen and treat the patient before progression. The present study deals with the screening of cervical cancer which included a sample of 167 women with abnormal symptoms like excessive white discharge, postmenopausal bleeding, postcoital bleeding, intermenstrual bleeding, women with abnormal VIA, VILI and pap smear. Further proceeded with the help of colposcopy and biopsy in women with above mentioned symptoms and abnormal papsmear or VIA/VILI. Based on the results obtained, we calculated the sensitivity and specificity of two scores (reids and swede) and compared it with biopsy. Regarding age distribution, majority were women more than the age of 40 (109/167). Carcinoma cervix was prevalent in women more than 40 years. Based on the clinical complaints, majority of patients had excessive white discharge (69/167) followed by postmenopausal bleeding (47/167). Based on the theory, postmenopausal bleeding is highly predictive and pointing towards cancer cervix. Postcoital bleeding also noted in 10 among 16. The present study revealed that the specificity of 98.9% when swede score was more than or equal to 8. No CIN 2+ lesions were noted when the swede score was less than 5. But when the score was reduced to 5, sensitivity reaches 100% at the specificity of 91.3% which was decreased. The negative predictive value was 100% when the score was reduced to 5.The association of swede score with cytology is statistically significant. CONCLUSION: Thus, it was concluded that both scores performed well in this hospital based study on a selected population referred to colposcopic clinic.From the present study, it is evident that SWEDE score of 8 or more has good specificity and can be used for performing direct excisional procedure as a “see and treat” method at this cutoff. Hence LESION SIZE parameter included in SWEDE SCORE act as a good predictor of high-grade lesions. ❖ This may be the preferred method for the management of high grade CIN because it reduces the number of visits and failure to receive treatment. ❖ The main strength of the study is that biopsies were taken for all subjects irrespective of the presence or absence of lesion in colposcopy, eliminating the verification bias.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 221916057 |
| Uncontrolled Keywords: | Comparative Diagnostic Validity, Two Colposcopic Indices-Reids Index, Swede Score, Cervical Histology. |
| Subjects: | MEDICAL > Obstetrics and Gynaecology > MEDICAL > Obstetrics and Gynaecology |
| Depositing User: | Subramani R |
| Date Deposited: | 03 May 2021 09:44 |
| Last Modified: | 27 Nov 2023 05:28 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/15710 |
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