A Study of Maternal Risk Factors Associated with Development of Neonatal Jaundice: A Cross Sectional study

Soumya, P (2022) A Study of Maternal Risk Factors Associated with Development of Neonatal Jaundice: A Cross Sectional study. Masters thesis, Stanley Medical College, Chennai.

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Abstract

BACKGROUND: Neonatal jaundice is one of the most common neonatal admissions in the hospital. About 80% of preterm newborns and 60% of term newborns will develop neonatal jaundice. It is of two types physiological jaundice and pathological jaundice. Physiological jaundice usually appears after 24 hrs of life, increase in bilirubin is less than 5mg/dl/day. It is clinically not detected after 14 days of life. It does not require any treatment. Physiological jaundice develops due to increased destruction of fetal haemoglobin resulting in raised bilirubin level, low capability of hepatocytes, high workload on hepatoventric circulation. Pathological jaundice develops within 24 hrs of life and rise in serum bilirubin level is more than 5mg/dl/day. It requires immediate treatment. Failure of early identification and immediate treatment will lead to adverse complications like kernicterus. Kernicterus is bilirubin encephalopathy which increases featal mortality and fetal morbidity leading to long term complications like hearing problems, gait disturbances and intellectual disability. Various maternal factors are known to influence the development of neonatal jaundice. Thorough knowledge about these factors helps in prevention, early identification and development of complications in neonatal jaundice. OBJECTIVE OF THE STUDY: To identify the relationship between maternal risk factors and neonatal jaundice and helps us to find the maternal risk factors that are modifiable thereby reducing the prevalence of neonatal jaundice and neonatal admissions in hospital. MATERIALS AND METHODS: This is an observational type of study where 250 postpartum mothers with term newborns diagnosed with neonatal jaundice requiring intervention phototherapy in Govt RSRM lying in hospital, Chennai were included in the study. The study spanned over a period of one year. The patients were selected based on inclusion and exclusion criteria. The relevant data were collected and analyzed. RESULTS: Among 250 postpartum mothers whose babies with neonatal jaundice requiring intervention phototherapy were included in this study and was found that maternal risk factors like gestational hypertension, gestational diabetes mellitus and maternal haemoglobin shows highly significant association with development of neonatal jaundice. CONCLUSION: This study explains that there is statistical association between maternal risk factors like geatational hypertension, gestational diabetes mellitus, maternal haemoglobin and development of neonatal jaundice. Hence early identification and treatment of these maternal risk factors help in prevention of development of neonatal jaundice requiring intervention phototherapy.

Item Type: Thesis (Masters)
Additional Information: 221916068
Uncontrolled Keywords: Maternal Risk Factors Associated, Development, Neonatal Jaundice.
Subjects: MEDICAL > Obstetrics and Gynaecology
> MEDICAL > Obstetrics and Gynaecology
Depositing User: Subramani R
Date Deposited: 03 May 2021 09:41
Last Modified: 03 Dec 2023 06:18
URI: http://repository-tnmgrmu.ac.in/id/eprint/15699

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