Anirudh Srinivas, V (2023) Conicity Index as a Screening Tool for Carsiovascular Risk Factors in Indians. Masters thesis, Stanley Medical College, Chennai.
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Abstract
BACKGROUND AND OBJECTIVES: Anthropometric indices and body measurements are used as indicators of measures of body fat distribution since axial computed tomography (the gold standard to assess body fat distribution) is expensive as well as time-consuming. The most appropriate anthropometric index to assess body fat distribution still remains unclear. Measures of centralized adiposity like Waist circumference (WC) Waist-To-Hip-Ratio (WHR), etc., are superior to Body Mass Index (BMI) which is the most commonly used and available index, indetecting cardiovascular risk factors. Conicity Index (CI) is relatively unknown anthropometric index which allows for comparison of abdominal adiposity between individuals of varying height, weight, and populations, as the formula contains the height, weight and waist circumference. Waist circumference, Waist-to-hip ratio et care good representatives of abdominal obesity, have shown variable results in predicting cardiovascular risk factors among different races and populations globally. In Western populations CI as a predictor of cardiovascular risk factors has been studied but there are very few studies on Indians on the use of CI for prediction of cardiovascular risk factors. OBJECTIVES: To study the utility of Conicity Index as a screening tool for cardiovascular risk factors in Indians and compare CI with other anthropometric measures like BMI, WHR, WC etc. as a correlate of cardiovascular risk factors. METHODS: Subjects above the age of 18 years availing the Master Health Checkup facility at Government Stanley Medical College and Hospital were taken into the study. Anthropometric measurements like waist circumference, hip circumference, weight and height were taken. A brief medical history was taken and physical examination was done. Fasting blood glucose, post prandial blood glucose, fasting lipid profile, and serum TSH was tested. Statistical analysis of the data was done to arrive at a cut-off of CI as a screening tool for cardiovascular risk. RESULTS: A positive but weak correlation was found between CI and cardiovascular risk. The cut-off value of CI to enable an action level to prevent cardiovascular mortality was 1.23. A stronger correlation was found between WHtR and cardiovascular risk. WHtR was found to be a better screening tool in men and women. CI also correlated strongly with waist circumference, PPBS, SBP. INTERPRETATION AND CONCLUSION: A better correlation was found between WHtR and cardiovascular risk in men and women, signifying that increasing waist circumference, and therefore abdominal obesity has a strong role in the causation of cardiovascular morbidity and mortality. These findings to inculcate the fact that measures of abdominal obesity are required to determine the metabolic risk factors of an individual to start on primary preventive strategies against cardiovascular diseases, hence enabling us physicians to reduce the global cardiometabolic risk.
| Item Type: | Thesis (Masters) |
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| Additional Information: | Reg.No.200120101031 |
| Uncontrolled Keywords: | Obesity, abdominal obesity, cardiovascular risk factors. |
| Subjects: | MEDICAL > General Medicine > MEDICAL > General Medicine |
| Depositing User: | Subramani R |
| Date Deposited: | 02 May 2021 14:28 |
| Last Modified: | 20 Mar 2024 07:02 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/15586 |
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