Orbital involvement in fungal sinusitis.

Ramanathan, C (2010) Orbital involvement in fungal sinusitis. Masters thesis, Christian Medical College, Vellore.


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Fungi are eukaryotic organisms comprising moulds, yeasts, mushrooms and similar organisms. More than 1,00,000 species of fungi have been described. Of these, only about 0.1% are recognized as human pathogens, although the number capable of producing human disease continues to increase. The incidence of mycotic infections and the number and diversity of pathogenic fungi have increased dramatically in recent years. Although many humans are colonized by fungi, an intact immune system prevents subsequent infection. The pathogenicity of fungi is poorly understood. Fungi may cause disease by establishing an infection, elaborating toxin(s),or by inducing allergic response(s). In conclusion, orbital involvement is much more common in occurrence in invasive fungal sinusitis compared to non invasive fungal sinusitis. Clinical and endoscopic examination is an essential part of assessing orbital involvement. Radiological findings in invasive fungal sinusitis evidently bear no correlation with clinical findings. Indeed, despite the high prevalence of ocular involvement in patients with invasive fungal sinusitis, the radiological findings are often unremarkable. A high index of suspicion and early biopsy and fungal culture testing in suspected patients helps early identification and planning of subsequent management.

Item Type: Thesis (Masters)
Uncontrolled Keywords: fungal sinusitis; Orbital involvement
Subjects: MEDICAL > Otolaryngology
Depositing User: Devi S
Date Deposited: 12 Jul 2017 06:33
Last Modified: 12 Jul 2017 06:33
URI: http://repository-tnmgrmu.ac.in/id/eprint/1521

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