Soundarya Rahini, C (2021) Long Term Outcome of patients with Keratoconus who have undergone Corneal Collagen cross linking in one eye and the status of the fellow eye. Masters thesis, Institute of Ophthalmology, Joseph Eye Hospital, Tiruchirappalli.
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Abstract
This current study aimed at assessing the safety and efficacy of corneal collagen cross linking (C3R) procedure in patients with progressive keratoconus at a tertiary eye care hospital in a specific setting; various parameters were followed-up for a period of one year, comparing these with the pre operative mean values and the following conclusions were made. The uncorrected visual acuity and the best corrected visual acuity improved from the mean baseline values in all the operated eyes in all three groups (A, B and C); in the fellow unoperated eye (Groups A and B), the mean UCVA and BCVA were either stable or reduced by the end of one year follow up. This shows stability of vision after the C3R procedure. The study also observed no statistically significant difference in pre and post operative cylinder value and spherical equivalent in all operated eyes, suggesting halt of disease progression, and fellow unoperated eyes showed either stable or increase in cylinder and spherical equivalent values by end of one year follow up. All the topographic values (K1, K2 and Average K) showed a gradual flattening in all follow up visits in all operated eyes in all three groups when compared to that of the unoperated eyes, where there was either stable value or gradual steepening was noted by end of one year follow up. All the visual and topographic indices observed over the period of one year after the procedure showed a trend of either halting or partially reversing the disease process in operated eyes, when compared to that of the fellow unoperated eyes. Thus, corneal collagen cross-linking with riboflavin appears to be a simple, safe and an effective modality of treatment for progressive keratoconus, with good success rate and minimal incidence of complications. However, a study on a larger number of patients with longer follow-up is required for assessing the longevity of this procedure and its long- term side effects.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 221803404 |
| Uncontrolled Keywords: | Long Term Outcome, Keratoconus, Corneal Collagen, cross linking in one eye, status of the fellow eye. |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Subramani R |
| Date Deposited: | 11 Apr 2021 12:47 |
| Last Modified: | 09 Jan 2022 13:33 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/14617 |
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