Thilagavathi, N (2020) Role of Dermatoglyphics in malignant and Potentially Malignant Disorders of the oral cavity: A Cross Sectional study. Masters thesis, Tamil Nadu Government Dental College and Hospital, Chennai.
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Abstract
AIM OF THE STUDY: The aim of the present study is to identify the genetic predilection of malignant and potentially malignant disorders based on the dermatoglyphics pattern. OBJECTIVES: 1. To compare the dermatoglyphics of A) patients with malignant and potentially malignant disorders of oral cavity, B) patients with habits but without lesion, C) patients without habit and 2. To analyse which dermatoglyphic pattern is common among the patients with malignant and potentially malignant disorders. METHODS: Fingerprints and palm prints were studied in 300 patients from Tamilnadu Government Dental College and Hospital were studied, who were randomly divided into three groups: (A) 100 subjects with OSF, OL and OSCC, (B) 100 patients with habits and no lesions, and (C) 100 healthy controls, for the purpose of finding patterns that could identify patients with PMDs and OSCC. Finger and palm prints were taken by the ink method. Prints were analysed. RESULTS: The results were tested for statistical significance. Weighted kappa statistics were used to evaluate the inter- and intra-observer agreement. It was observed that the arch pattern (9.3%) was pre-dominant in group A compared with control Group B(3.4%) and group C(0.6%) with a decrease in whorl pattern (39.5%) in Group A when compared with the controls group B(45.7%) and group C(50.7%) and the difference was statistically significant (P < 0.01). The study group demonstrated an decrease in the mean total finger ridge count and ATD angle as compared to the controls and the result was found to be highly significant (P < 0.05). CONCLUSION: Dermatoglyphics can be implemented as a screening tool in patients with PMDs and OSCC. Thereby, we can identify patients at increased risk for oral cancer so that risk reduction measures or earlier therapy may be instituted.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Dermatoglyphics, Oral leukoplakia, Oral Squamous cell carcinoma, Oral Submucous fibrosis. |
| Subjects: | DENTAL > Oral Medicine and Radiology |
| Depositing User: | Subramani R |
| Date Deposited: | 25 Feb 2021 02:59 |
| Last Modified: | 25 Feb 2021 16:27 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/14513 |
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