A Descriptive study of Clinical, Pathological, Radiological Staging of Head and Neck Malignancies

Ramya, Moturu (2020) A Descriptive study of Clinical, Pathological, Radiological Staging of Head and Neck Malignancies. Masters thesis, Stanley Medical College, Chennai.


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INTRODUCTION: Head and Neck Malignancy (HNM) is a recognized major public health concern all over the world. They are amongst the commonest malignancy in India and accounts for up to 20% cancer burden in India. In India 25% of all male cancers and 10% of female cancers are reported to be head and neck cancers. 57.5% of global HNC do occur in Asia, specially in India. 60-80% cases in India are diagnosed with later stages of cancer reducing the survival rate. Squamous cell cancer constitutes the most common head and neck malignancy and is related to tobacco and/or alcohol usage. Non-squamous malignancy includes thyroid cancer, salivary gland cancer and sarcomas. These malignancies are not associated with tobacco and/or alcohol usage. AIMS AND OBJECTIVES: 1. To compare the results of clinical and pathological and radiological staging in head and neck malignancies and to examine patterns and ramifications of the disparity between staging methods. 2. Comparison of tumour extent with radiological and pathological staging. 3. Demographic features of head and neck malignancy. MATERIALS AND METHODS: STUDY POPULATION: 80. STUDY DESIGN: Prospective study. STUDY PERIOD: September 2018- September 2019. STUDY DURATION: 12 months. PLACE OF STUDY: Department of ENT, Government Stanley Medical College, Chennai. INCLUSION CRITERIA: 1. Age : > 18 & < 75 years. 2. All head and neck malignancies presenting to ENT department. EXCLUSION CRITERIA: 1. Age : < 18 and > 75 yrs. 2. Primary malignancy else where (not head and neck) with neck secondaries. 3. CA of head and neck malignancy with post chemoradiotherapy. 4. Metachronus or synchronous malignancy, 5. Neurosurgical tumours, 6. Benign tumours of larynx. RESULTS: A descriptive study of clinical pathological and radiological staging of Head and Neck Malignancy among eighty samples for one year revealed the following results. It was a prospective study with the age group between 18 to 75 years. CONCLUSION: There is a substantial difference between clinical and pathological staging for T and N categories. There is a significant difference between pathological and radiological staging for T and however no significant difference for N categories. There is no significant difference between clinical and radiological staging for T and N category. Since none of the study case had distant metastasis M category was not analysed. Regarding tumour extent there is a significant difference between pathological and radiological assesments. Postoperative pathological staging gives accurate assessment when compared to radiology. On demographic analysis head and neck cancer in our study are more common in males of age group 61-70yrs, who are smokers and belonging to low socioeconomic status. Most of the head and neck cancers in our study involve larynx primarily.

Item Type: Thesis (Masters)
Additional Information: 221714053
Uncontrolled Keywords: Clinical, Pathological, Radiological Staging, Head and Neck Malignancies, Descriptive study.
Subjects: MEDICAL > Otolaryngology
Depositing User: Subramani R
Date Deposited: 15 Feb 2021 03:11
Last Modified: 15 Feb 2021 03:11
URI: http://repository-tnmgrmu.ac.in/id/eprint/14219

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