Vandhana, T (2020) Swept Source Optical Coherence Tomography Findings of Pachychoroid Spectrum of Diseases in patients with Unilateral Acute Central Serous Chorioretinopathy. Masters thesis, Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Madurai.
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Abstract
INTRODUCTION: Central serous chorioretinopathy (CSCR) is the fourth most common retinopathy after age-related macular degeneration, diabetic retinopathy and branch retinal vein occlusion. CSCR occurs in males in the age group of 20 to 50 years. There is no underlying proven pathophysiologic mechanism for CSCR. It is thought to occur due to hyper permeable choroidal capillaries in association with retinal pigment epithelium causing serous detachment of neurosensory retina. Recurrence rate of CSCR is about 33% and some texts show the recurrence rate of about 50%. In 1866, the disease was first recognized by Albrecht Von Grafe and named as central recurrent retinitis. It has been reported under a variety of names such as idiopathic flat detachment of the macula by Walsh et al, central angiospastic retinopathy by Gifford et al, and central serous retinopathy by Straatsma et al. Gas et al, named the condition as Idiopathic central serous chorioretinopathy in 1967. AIM AND OBJECTIVE: To describe retinal and choroidal findings in both eyes of patients with unilateral acute central serous chorioretinopathy (CSCR) with a focus on pachychoroid spectrum of disorders using swept source optical coherence tomography (SS OCT). METHODOLOGY: Prospective observational study on patients with unilateral acute CSCR using SS OCT presenting to Retina department, Aravind Eye Hospital, Madurai during the period of December 2017 to November 2018. All 127 patients underwent visual acuity testing, IOP, anterior & posterior segment examination and SS OCT. SS OCT findings of thinning of choriocapillaries, pachyvessels and choroidal thickness in both eyes were noted. RESULTS: Among 127 patients, choroidal thickness of ≥300μm was seen in 98.4% of affected eyes. The mean choroidal thickness in CSCR eyes were 431.6μm and normal eyes were 387.51μm showing significant difference in choroidal thickness between affected and normal eyes. Dilated vessels were seen in 25.2% of CSCR eyes and 6.3% in normal eyes.Thinning of choroidal capillaries were seen in 24.4% CSCR eyes compared to normal eyes which is 7.1%.This showed that there is an association of pachyvessel and thinning of choriocapillaries with CSCR. CONCLUSION: In this study, we observed an increase in choroidal thickness of > 300μm, dilated vessels in choroid and thinning of choriocapillaris in both eyes of patients with unilateral acute CSCR. This suggests most often CSCR is found to be a part of pachychoroid spectrum of disorders.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 221713462 |
| Uncontrolled Keywords: | Swept Source Optical Coherence Tomography, Pachychoroid Spectrum, Unilateral Acute Central Serous Chorioretinopathy. |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Subramani R |
| Date Deposited: | 14 Feb 2021 16:39 |
| Last Modified: | 14 Feb 2021 16:39 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/14212 |
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