Deborah Rinita, R (2020) Evaluation of Tear Film and Ocular Surface in Diabetes Mellitus patients attending a Tertiary Care Medical College Hospital. Masters thesis, Karpaga Vinayaga Institute of Medical Sciences and Research Centre, Kanchipuram.
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Abstract
PURPOSE: This study was performed to assess tear film and ocular surface irregularities in diabetes mellitus patients and to study the prevalence of dry eye in a hospital-based population. AIMS AND OBJECTIVES: 1. To assess tear film and ocular surface abnormalities in diabetic patients presenting to the ophthalmology department. 2. To study the common symptoms of dry eye in diabetics in a rural Indian population. 3. To correlate dry eye syndrome with the duration of diabetes. 4. To study the prevalence of dry eye in diabetics in a rural Indian population. MATERIALS AND METHODS: In this cross-sectional study 200 patients with diabetes mellitus above 40 years of age were consecutively selected. All subjects were assessed with demographic profile, symptom elicitation, Schirmer test and examined in slit lamp to assess dry eye with tear meniscus height, tear film break up time, staining patterns in conjunctiva and cornea with fluorescein and lissamine green staining. Indirect ophthalmoscopy was done in all subjects to diagnose diabetic retinopathy. Grading was done based on symptoms and clinical tests done and dry eye was diagnosed. RESULTS: Of 200 subjects, 64 patients (32%) suffer from tear film and ocular surface disease, dry eye. It was more common in older patients with increased duration of diabetes. Higher prevalence in labourers and industrial workers (36%), also in male (55.5%) patients compared to females (44.5%) was seen in this study. Grittiness was the most common symptom (42%) followed by watering (39%) and irritation (31%) All demographic variables except gender and occupation had significant association with P < 0.001. Schirmer, TBUT, staining of conjunctiva and cornea had statistically significant association with dry eye in this study with P < 0.001. CONCLUSION: The prevalence of dry eye was 32% in this study. Tear film abnormalities and ocular surface irregularities are features of dry eye. There was association of dry eye with diabetes. Grittiness was the commonest symptom. Examination for dry eye for early diagnosis and treatment to prevent complications must be an integral part of diabetic eye evaluation.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 221713551 |
| Uncontrolled Keywords: | Tear film, Diabetes, Dry eye, Schirmer, TBUT, Lissamine green. |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Subramani R |
| Date Deposited: | 14 Feb 2021 15:24 |
| Last Modified: | 14 Feb 2021 15:24 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/14200 |
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