Reshmi, Mathews (2020) Role of choroidal thickness and psychological stress in Central serous chorioretinopathy: A Cross sectional study. Masters thesis, Christian Medical College, Vellore.
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Abstract
INTRODUCTION: Central serous chorioretinopathy (CSCR) is a chorioretinal disorder with systemic associations and multifactorial etiology. It is characterized by serous detachment of the neurosensory retina, which is usually located at the posterior pole. Patients with CSCR present with relative central scotoma, metamorphopsia, micropsia, dyschromatopsia and blurring of vision. Fundus examination shows a well-demarcated, oval-shaped area of neurosensory retinal detachment at the posterior pole. The disease is usually self-limiting, and resolves spontaneously in most of the patients within a period of about three months, without significant visual loss. However, many patients develop recurrence, or develop chronic disease, leading to RPE atrophy and pigmentation in the macular area, with varying degrees of visual loss. OBJECTIVES: The objective of our study was to evaluate the role of choroidal thickness and psychological stress in patients with Central Serous Chorioretinopathy (CSCR). METHODS: Patients with unilateral CSCR, and age and gender-matched controls without CSCR, who met the eligibility criteria, were enrolled in the study after informed consent. Data regarding demographic profile and risk factors were documented. All patients had a complete ophthalmological examination and relevant investigations, including a Swept Source OCT scan of the macula. Subfoveal choroidal thickness (SFCT) of both eyes of all the participants was measured using a standard protocol. Psychological stress was assessed using Cohen Perceived Stress Scale (PSS-10). The data were collated and analyzed using Independent samples t-test, Chi-square/ Fisher’s exact test and Pearson’s correlation coefficient, as appropriate. RESULTS: The mean SFCT of CSCR eyes was significantly greater than that of control eyes (P<.01). The mean SFCT of fellow eyes was also significantly higher than that of control eyes (P<.01). There was no statistically significant difference in the mean SFCT between CSCR eyes and fellow eyes (P = .24). The mean stress score of patients with CSCR was significantly higher than that of age and gender-matched controls (P < .01). We found a strong positive correlation between SFCT and stress scores of the study population (r= 0.85, P<. 01). significantly higher than that of age and gender-matched controls (P < .01). We found a strong positive correlation between SFCT and stress scores of the study population (r= 0.85, P<. 01).
| Item Type: | Thesis (Masters) |
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| Additional Information: | 221713304 |
| Uncontrolled Keywords: | Central serous chorioretinopathy, choroidal thickness, psychological stress. |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Subramani R |
| Date Deposited: | 14 Feb 2021 14:15 |
| Last Modified: | 14 Feb 2021 14:15 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/14192 |
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