Gitanjali, V C (2020) Etiological Profile and Clinical Patterns of Uveitis. Masters thesis, Tirunelveli Medical College, Tirunelveli.
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Abstract
BACKGROUND: Uveitis is defined as inflammation of the uvea. The inflammatory process primarily affects the uvea with subsequent damage to the retina, optic nerve, sclera and vitreous. Uveitis can be classified based on the anatomical site involved [Standardization of Uveitis Nomenclature (SUN)], or clinical course (acute, chronic, or recurrent), or etiology (infectious or noninfectious), or pathology (granulomatous or nongranulomatous). AIM OF THE STUDY: To study the etiological profile and clinical patterns of uveitis. MATERIALS AND METHODS: Study Design: Cross sectional study. Sample Size: 50. Source of Data: A series of patients with uveitis attending the ophthalmology outpatient department in tirunelveli medical college for a period of 18 months from October 2017 to April 2019. Inclusion Criteria: ◈ All patients with anterior, intermediate, posterior and panuveitis. ◈ Both male and female. ◈ Any age group with uveitis. Exclusion Criteria: ◈ Uveitis with trauma as the etiology. ◈ Uveitis following intraocular surgery. 50 patients with uveitis were enrolled in the study after getting informed consent. A detailed history regarding age, occupation, residence, known systemic diseases past or present was elicited. Patients were questioned about backache/joint problems, skin diseases, respiratory diseases, neurological diseases, gastrointestinal diseases, oral and genital ulcers and sexually transmitted diseases. A thorough ocular examination included best corrected visual acuity (BCVA), slit lamp examination (SLE), indirect ophthalmoscopy (IDO), applanation tonometry (AT), gonioscopy. In addition, fundus fluorescin angiography (FFA), optical coherence tomography (OCT)B scan ultrasonograph were performed if needed. RESULTS: In my study adults (70%) were most commonly affected due to uveitis. The age of patients ranged from 30-60 years. The mean age at presentation was 39.7± 14.06 yrs. Children (1%) and elderly (14%) were less commonly affected. there was no sexual preponderance. Unilateral uveitis (70%) was more common than bilateral (30%). Anterior uveitis was the most common anatomical type of uveitis (64% n=32) followed by panuveitis (16% n=8), posterior (14%n=7) and intermediate uveitis (6% n=3). Chronic uveitis (56%) was more common than acute uveitis (28%). 42% of the uveitis was non granulomatous and 38% of the uveitis was granulomatous .32% (n=16)of the uveitis was due to non infectious etiology and 36%(n=18) of the uveitis was due to infective etiology. CONCLUSION: 1. Anterior uveitis is the most common anatomical type of uveitis. 2. Idiopathic uveitis is the most common type of anterior uveitis. 3. Pars planitis is the most common cause of intermediate uveitis. 4. TB related posterior uveitis is the most common cause of posterior uveitis. 5. Vogt Koyanagi Harada disease and TB related panuveitis are the most common causes of pan uveitis. 6. Infective uveitis is more common than non infective uveitis. 7. Infective uveitis is more common in posterior and panuveitis. 8. Tuberculosis is the most common form of infectious uveitis. 9. Spondyloarthropathy is the most common cause of non-infective cause of uveitis.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 221713252 |
| Uncontrolled Keywords: | Uveitis, Anterior, Intermediate, Posterior and Panuveitis. |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Subramani R |
| Date Deposited: | 14 Feb 2021 13:06 |
| Last Modified: | 14 Feb 2021 13:06 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/14184 |
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