Harshini, G V (2020) An Observational study to Determine the Association between Posterior Vitreous Detachment and Proliferative Diabetic Retinopathy. Masters thesis, Madurai Medical College, Madurai.
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Abstract
INTRODUCTION: As diabetic retinopathy is the most common cause of blindness it should be regularly followed up for the progression. Patients having the borderline severe non proliferative disease should be carefully monitored and early pick up of proliferative diabetic retinopathy disease will prevent permanent visual loss. While assessing the progression some of the factors acts as a protective factor against the proliferative disease in which PVD is one of the important factor. As vitreous attachment is the scaffold for the new blood vessel to grow and cause traction leads to complications such as vitreous haemorrhage, tractional retinal detachment, neovascular glaucoma. Complete PVD is the protective factor for complications of PDR but there is high risk of PDR in incomplete PVD as there is availability of scaffold for new vessels to proliferate. So in this study PVD and its association with complications of PDR had been elicited which gave results for assessing further progression. In our study, we had taken one fifty patients with proliferative diabetic retinopathy classified based on EDTRS classification. AIMS AND OBJECTIVES: The aim of this study is to observe the association between posterior vitreous detachment and proliferative diabetic retinopathy. MATERIALS AND METHODS: Study Design: Non randomized, cross sectional (prevalence) study Intended Sample Size: 50 patients. This study includes type 2 diabetic patients with DR who were visiting outpatient department of GRH, Madurai for diabetic retinopathy screening between February 2019 and September 2019. Study Period: 8 months (February 2019 to September 2019). Selection of Subjects: A total of 50 type 2 diabetic patients with DR of age 40 -70 years visiting OPD of ophthalmology GRH, Madurai who were within the following inclusion and exclusion criteria. INCLUSION CRITERIA: 1. Type 2 diabetic patients with DR. 2. Age between 40-70 years. EXCLUSION CRITERIA: 1. Comorbid conditions such as hypertension, blood dyscrasia, collagen vascular disorder, sarcoidosis. 2. Extremes of refractive error and high axial length. 3. Ocular comorbidities such as glaucoma, uveitis. 4. Previous retinal photocoagulation and intravitreal injections. 5. Previous h/o trauma, intraocular surgeries, electroconvulsive therapy. 6. Carotid occlusive disease excluded by physical examination. 7. Patients in whom fundus examination and FFA could not be done. RESULTS: In our study we had studied the age group from 40 to 70 years in that we had arrived the correlation of age and PVD and found out that the mean age for PVD was 60 years. there was a positive correlation between posterior vitreous detachment grading with the severity of diabetic retinopathy and their complications. With the summary of age group of mean age of 60 years 62% of the population affected are male having higher grades of diabetic retinopathy of 54% and 70% in right and left eye,55% had posterior vitreous detachment out of that complete posterior vitreous detachment is 44%. Comparing visual acuity with the posterior vitreous detachment in right eye 60% had PVD in that 48% had complete PVD out of that 75% had better vision with the significant P value of 0.002 in left eye 50% had PVD in that 40 % had complete PVD out of that 70% had better vision with significant P value of 0.043. CONCLUSION: From our study we had arrived at a positive correlation that patients having complete posterior vitreous detachment had less complications of proliferative diabetic retinopathy had better vision than patients without having posterior vitreous detachment and partial vitreous detachment.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 221713102 |
| Uncontrolled Keywords: | Posterior Vitreous Detachment, Proliferative Diabetic Retinopathy. |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Subramani R |
| Date Deposited: | 14 Feb 2021 08:54 |
| Last Modified: | 14 Feb 2021 08:54 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/14173 |
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