Kaowshalyaa, A (2020) A Clinical study on Visual Evoked Potential Changes and Visual Field Defects in COPD Patients: A Cross Sectional study. Masters thesis, Stanley Medical College, Chennai.
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Abstract
INTRODUCTION: Chronic obstructive pulmonary disease (COPD), is a public health problem seen worldwide being the fourth largest international cause of death and second largest cause of death in India. It has been identified to have multisystem involvement with significant extra pulmonary manifestations including central and peripheral neuropathy. OBJECTIVE: To assess visual evoked potentials (VEP) abnormalities and visual field defects in COPD patients and to correlate the changes with severity of COPD with no clinical evidence of visual impairment or peripheral neuropathy. METHODS: Study comprised of 96 COPD patients (46 – 65 years). Duration of illness, smoking pack years and spirometric indices (FEV1%, FEV/FVC) were assessed. As per WHO GOLD criteria severity of COPD was classified. VEP of all patients were recorded. Visual fields of all patients were recorded. RESULTS: Observations revealed the latency of N75 and P100 were prolonged (P < 0.01) and the amplitude of P100 was reduced significantly (P < 0.01) in all patients and correlated significantly with increasing severity of COPD. Visual fields revealed decreased Mean Sensitivity (P < 0.01) and increased Mean Deviation (P < 0.01) and correlated significantly with increasing severity of COPD. CONCLUSION: Significant VEP abnormalities and visual field changes was observed in COPD patients. Observation suggested that hypoxemia of COPD, by causing changes in arterial blood gases and ventilation-perfusion imbalance may be implicated for the impairment in visual evoked responses and visual field changes.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 221713051 |
| Uncontrolled Keywords: | Chronic Obstructive Pulmonary Disease (COPD), Visual Evoked Perfusion (VEP), Visual field, hypoxemia. |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Subramani R |
| Date Deposited: | 14 Feb 2021 07:39 |
| Last Modified: | 14 Feb 2021 07:39 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/14168 |
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