A Clinical study on Role of Radioimaging like CT/ MRI in Diagnosis and Management of Orbital Lesions

Nisha, C (2020) A Clinical study on Role of Radioimaging like CT/ MRI in Diagnosis and Management of Orbital Lesions. Masters thesis, Madras Medical College, Chennai.

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Abstract

INTRODUCTION: Imaging plays a vital role in characterization of orbital lesions in terms of site of lesion, extent and involvement of vital structures. Understanding of the imaging finding for various non traumatic orbital conditions like inflammation, infection, neoplasia is very crucial for the diagnosis and treatment of the condition in order to avoid visual loss1. Imaging techniques like CT/ MRI has revolutionized the diagnosis of orbital lesions. CT SCAN is first line imaging tool for diagnosing orbital lesions in acute conditions, with MRI having an important role in diagnosis of soft tissue conditions. Although imaging studies can demonstrate tissue definition, pathological conditions can be assessed by tissue studies. Therefore a combined clinical, radiological and histology finding is essential for arriving at the diagnosis. AIM OF THE STUDY: 1. To study the role of CT, MRI in the diagnosis of orbital lesions. 2. To correlate the imaging with histopathological features MATERIALS AND METHOD: This prospective study consisting of 50 patients was done at Orbit and Oculoplasty department, RIOGOH for one year period from January 2018 - December 2018. RESULTS: majority(34%) were in the age group of 39-58 years of age. Inflammatory lesion was the most common presenting condition and among the inflammatory condition, orbital cellulitis was the most common. Dermoid cyst was the most common benign lesion and also most common congenital condition presented. capillary hemangioma treated with beta blockers showed significant improvement. Retinoblastoma was the most common intraocular malignant lesion. And there was a statistical significant association found between presence of calcification and retinoblastoma. Adenoid cystic carcinoma was associated with bone destruction. Out of 18 cases which were subjected to biopsy, 17 patients had clinical pathological correlation. 88% had clinico radiological correlation. The association between RAPD and radiological optic nerve involvement was found to be statistically significant. CONCLUSION: This study highlights the role of comprehensive history taking, and appropriate imaging technique to decide treatment option. It was noted that there was significant disparity between clinical and radiological report and, relatively less disparity between histopathological and clinical diagnosis. Clinical diagnosis and imaging report can narrow down the differential diagnosis but diagnosis of orbital lesions ultimately requires the histological confirmation.

Item Type: Thesis (Masters)
Additional Information: 221713007
Uncontrolled Keywords: Orbital lesions, imaging studies, clinico histopathological correlation, clinicoradiological correlation.
Subjects: MEDICAL > Ophthalmology
Depositing User: Subramani R
Date Deposited: 14 Feb 2021 07:09
Last Modified: 14 Feb 2021 07:09
URI: http://repository-tnmgrmu.ac.in/id/eprint/14165

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