A study of factors determining outcome of acute renal failure patients requiring hemodialysis.

Pabolu, Surendra Kumar (2012) A study of factors determining outcome of acute renal failure patients requiring hemodialysis. Masters thesis, PSG Institute of Medical Sciences and Research, Coimbatore.

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Abstract

BACKGROUND : Acute renal failure is a common problem in critically ill patients and usually associated with significant morbidity and a high mortality rate. Despite advances in the management of critically ill patients with acute kidney injury (AKI), the prognosis is poor. AIM : To ascertain the causes and outcomes of acute renal failure requiring renal replacement therapy. DESIGN : A prospective observational study of patients with acute renal failure treated with IHD in one teaching tertiary care hospital from November 2010 to 31 Oct 2011 .The outcomes measured was hospital mortality and progression to ESRD and dialysis dependency Relationship between demographics, premorbidities and clinical parameters with outcome was studied. MEASUREMENTS AND RESULTS : One hundred and fourteen patients were included in the final analysis. Of the 114 patients, 49 died (42.98%), 61 (53.5%) recovered to have normal renal function or mild renal dysfunction and 4 patients (3.5%) progressed to end state renal disease (ESRD) The Mortality among patients admitted in ICU was 87.8%. Parameters directly related to ARF and found significant association with mortality by multivariate analysis were chronic liver disease, preexisting heart disease, requirement of mechanical ventilation, oliguria, sepsis, hepatorenal syndrome cardiogenic shock, admission in ICU. CONCLUSION : ARF in ICU was associated with a high mortality rate. Patients with poor outcome were presence of chronic liver disease, preexisting heart disease hepatorenal syndrome and mechanical ventilation cardiogenic shock,. Most of the hospital survivors were free from dialysis. Key words: Acute renal failure ; Intermittent haemodialysis ; Outcome predictors.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Acute renal failure ; Intermittent haemodialysis ; Outcome predictors.
Subjects: MEDICAL > Nephrology
Depositing User: Kambaraman B
Date Deposited: 11 Jul 2017 07:57
Last Modified: 11 Jul 2017 07:57
URI: http://repository-tnmgrmu.ac.in/id/eprint/1409

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