Thiruppathi Raja, G (2020) Solitary Nodule Thyroid: A Diagnostic Dilemma. Masters thesis, Tirunelveli Medical College, Tirunelveli.
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Abstract
INTRODUCTION: The solitary thyroid nodule may be defined as a discrete swelling in an otherwise impalpable gland. The incidence of solitary nodule in general population in South India is 9%. Solitary nodule of the thyroid has aroused interest because of its varied etiology and diverse clinical presentations. Clinically, solitary nodules fall into two categories. In the first, there is a certainty or grave suspicion of malignancy and in the second there is a smooth, firm, mobile nodule which is probably benign but carries a small but significant risk of being malignant. The critical issue is to determine whether the nodule is benign or malignant. AIM OF THE STUDY: To estimate the proportion of malignancy in Solitary Thyroid Nodule. MATERIALS AND METHOD: The study was conducted in Department of General Surgery, Tirunelveli Medical College during a period of 2 years from July 2015 to June 2017. All patients with solitary nodule were included in the study. Inclusion Criteria: All patients with solitary nodule were included in the study. Exclusion Criteria: Patients diagnosed as multinodular Goitre clinically or sonographically were excluded from the study. RESULTS: Frozen section studies were done for all 18 cases of follicular neoplasm out of which 15 cases were diagnosed as follicular adenoma and hence proceeded with hemithyroidectomy. 2 patients were diagnosed to have follicular carcinoma and one patient had papillary carcinoma hence these 3 patients underwent total thyroidectomy. The incidence of malignancy in our series is 17.3%. In our study 33% of solitary nodules in males proved to be malignant whereas in females only 16% of solitary nodules were malignant. CONCLUSION: FNAC is highly specific in diagnosing malignant lesion but lacks sensitivity. Frozen section studies had added additional value in differentiating follicular adenoma from follicular carcinoma which could not be done by FNAC. But definitive diagnosis is possible only with excision and postoperative histopathological examination of the nodule. Though FNAC is initial diagnostic modality of choice HPE remains final diagnostic proof. The incidence of malignancy is higher in case of Solitary Nodule Thyroid.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 221711369 |
| Uncontrolled Keywords: | Solitary Thyroid Nodule, Malignancy, FNAC, HPE, completion thyroidectomy. |
| Subjects: | MEDICAL > General Surgery |
| Depositing User: | Subramani R |
| Date Deposited: | 11 Feb 2021 02:42 |
| Last Modified: | 11 Feb 2021 02:42 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/14047 |
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