Clinical Profile of Solitary Nodule Goitre

Jagadeesan, N (2020) Clinical Profile of Solitary Nodule Goitre. Masters thesis, Thanjavur Medical College, Thanjavur.

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Abstract

INTRODUCTION: Thyroid diseases are common worldwide, affecting 3-5% of the population. They include enlargement of the gland which is diffuse and nodular, solitary nodule can be benign, malignant and inflammatory diseases. Solitary nodule is a single or discrete nodule confined to one lobe of the thyroid and the opposite lobe may not be visible or palpable (True solitary nodule) about 70%. Solitary nodule thyroid (SNT) presents in 1-3% of the adult population and is common in women. The incidence of malignancy is 12-15% and more chance of malignancy is in a cold and solid nodule. In patients younger than 25 or older than 60, the malignancy rate for thyroid nodule as high as 60% has been described. AIM OF THE STUDY: The main aim is to know the presentation, incidence of malignancy and the role of FNAC in Solitary Nodule Thyroid. MATERIALS AND METHODS: This is a prospective study of patients who had suffered from clinically palpable, solitary nodule thyroid diagnosed and treated at Thanjavur Medical College & Hospital except Recurring thyroid nodules and patients of age 12 years or less and Diffuse hyperplastic goiter. A total of 74 patients were selected and fundamental investigations like complete hemogram, blood sugar, urea, urine analysis, chest radiogram and neck radiogram were done. Differential diagnosis of the state of thyroid disorder was obtained by FNAC in all these patients. RESULTS: Females were apparently more and percentage of being 85% and 15% patients being male and the age group of 21-40 years old patients found be 54%. Swelling was experienced by all the patients (100%), while the symptom of pain was only experienced by only 20.2% of all patients. SNT show a laterality towards right lobe of 73% of patients. Euthyroid status was predominantly seen in 80% of the patients. From the findings of FNAC, it was evident that the most common disorder seen as colloid nodular goitre. As SNTs respond better to treatment and usually shows increased survival rate than other thyroid malignancies, prognosis is indispensable for follow-up treatments.

Item Type: Thesis (Masters)
Additional Information: 221711204
Uncontrolled Keywords: Solitary nodule thyroid, FNAC.
Subjects: MEDICAL > General Surgery
Depositing User: Subramani R
Date Deposited: 10 Feb 2021 16:33
Last Modified: 10 Feb 2021 16:33
URI: http://repository-tnmgrmu.ac.in/id/eprint/13996

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