Saravanan, R (2020) A Prospective study of Factors Influencing Seroma Formation in Modified Radical Mastectomy. Masters thesis, Kilpauk Medical College, Chennai.
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Abstract
BACKGROUND: Seroma, is the most frequent post operative complication after breast cancer surgery/modified radical mastectomy (MRM), developing in approximately 30% of cases. The pathophysiology and mechanism of seroma formation in breast cancer surgery remains controversial and not fully understood, as little attention has been paid in the literature to etiologic factors. To prevent seroma formation, it is important to estimate individual risk of seroma formation. AIM OF THE STUDY: To establish an association between various risk factors of seroma formation and to know whether the risk factors act independently or by synergism. METHODS: Patients with breast cancer undergoing Modified Radical Mastectomy were included in the study. The proportions were compared using Chi-square test of significance and the student “t” test was used to determine the statistical difference. The data was analyzed using SPSS package. RESULTS: 15 out of 49 patients, accounting for 30.6 %, developed seroma compared to patients without seroma formation. The mean age was 55 + 6.80 in seroma group, p value was 0.039. The mean duration of symptom was 9 + 4.10 in seroma group, p value was 0.023. 14 of 15 patients who had developed seroma were hypertensive, accounting for 57.1%, p value was significant 0.01. 8 of 15 patients who had developed seroma were diabetic, accounting for 73.5%, p value was significant 0.01. The mean BMI in seroma patients was 27.25 +2.45 (SD), p value was significant 0.0005. The mean drain Output on pod 1 was 196.33+ 30.03 in seroma group, p value was significant 0.0005. Mean drain removal day was 16 + 1.49, p value was significant 0.0005 in seroma group. Other variables studied had no statistical significance with respect to seroma formation. CONCLUSION: The factors influencing seroma formation following modified radical mastectomy for carcinoma breast were found to be Age, duration of symptoms, Hypertension, Diabetic, BMI, drain out put and drain removal day were having a significant association for seroma formation.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 221711161 |
| Uncontrolled Keywords: | Breast, carcinoma, mastectomy, seroma. |
| Subjects: | MEDICAL > General Surgery |
| Depositing User: | Subramani R |
| Date Deposited: | 10 Feb 2021 16:07 |
| Last Modified: | 10 Feb 2021 16:07 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/13991 |
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