Karthick, J (2020) A Prospective study of a Commonly Overlooked Cause of Surgical Site and Infection-Low HDL in Government Rajaji Hospital, Madurai. Masters thesis, Madurai Medical College, Madurai.
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Abstract
INTRODUCTION: SSI is the infection following surgery at surgical incision and surgical space. SSI can be superficial sometimes involving only skin or it can extend beyond subcutaneous tissue to facial planes and organ space. SSI are responsible for an increased economic burden to health care system including additional postoperative hospital duration and cost, increases morbidity to the patient. Surgical site infection (SSI) is most challenging to every surgeons and each and everybody is trying their methods to reduce the problem. AIM OF THE STUDY: The study was undertaken to assess whether preoperative lower HDL level is associated with increased risk for SSI. METHODOLOGY: A study population of 175 patients admitted in GRH in department of general surgery for elective hernia repair were taken. Pre-operative cholesterol values are monitored. All patients in study group underwent open hernia repair. Operative wounds were examined on the 2, 5, 8 postoperative day for SSI. RESULTS: Incidence of SSI in this study is 18.9% out of 175 patients 33 of them developed SSI. Out of this 18.9%, 12.6% falls in the low HDL group. P Value < 0.001 (significant). Out of 33 patients with SSI 9 developed deep infection 27%, out of 9 with deep infection 7 belong to low HDL 77%. P value 0.044 (significant), showing patients with SSI with low HDL are vulnerable to develop deep infection. CONCLUSION: Hypocholesterolemia is one of the forgotten factor whose consideration can lead to significant decrease in SSI. This study concludes hypocholesterolemia is a significant risk factor for SSI.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 221711110 |
| Uncontrolled Keywords: | Surgical site infection, risk factors, low HDL. |
| Subjects: | MEDICAL > General Surgery |
| Depositing User: | Subramani R |
| Date Deposited: | 10 Feb 2021 01:30 |
| Last Modified: | 10 Feb 2021 01:30 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/13969 |
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