A Comparative study of Palpatory Versus Image Guided Core Needle Biopsy in Breast Masses in Government Rajaji Hospital, Madurai

Kanmani, A (2020) A Comparative study of Palpatory Versus Image Guided Core Needle Biopsy in Breast Masses in Government Rajaji Hospital, Madurai. Masters thesis, Madurai Medical College, Madurai.

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Abstract

OBJECTIVES: Biopsy of palpable breast masses can be performed manually by palpation guidance or under imaging guidance. We conducted this prospective study to verify the superiority and determine the size of beneficial effect of image guided biopsy over palpation guided biopsy. METHODOLOGY: This is a prospective study comprising 60 patients with breast masses over a period from September 2018 to September 2019. In this present study, the clinical material consists of adult female patients attending out-patient department with palpable breast masses on examination and on radiological investigation usg showing BIRADS 4, 5 and patient with BIRADS 3 high risk, difficult to follow or patient anxious are included in the study. During this period 60 female patient agreed to participate in study and gave informed consent.21 patients reported as Birads IV,26 patients reported as Birads V,13 patients with Birads III who satisfy inclusion criteria are taken to study. Patients are randomised into two arms 30 each to image guided and palpatory guided biopsy with ratio of 1:1. RESULTS: Malignancy was found in 24 of 30 women in palpation guided biopsy arm and 20 of 30 women in image guided biopsy arm. Palpation guided biopsy had sensitivity, and negative predictive value (NPV) of 48, 100, 100, 27.8 per cent, respectively, for diagnosing breast cancer. Palpation guided biopsy group had a high repeat biopsy rate. Image guided biopsy had 85 per cent sensitivity and 100 per cent specificity. CONCLUSION: Our results showed that in palpable breast masses, image guided biopsy was superior to palpation guided biopsy in terms of sensitivity, false negative rate and repeat biopsy rates.

Item Type: Thesis (Masters)
Additional Information: 221711109
Uncontrolled Keywords: core needle Breast biopsy, breast mass, image guided, palpation guided.
Subjects: MEDICAL > General Surgery
Depositing User: Subramani R
Date Deposited: 10 Feb 2021 01:26
Last Modified: 10 Feb 2021 01:26
URI: http://repository-tnmgrmu.ac.in/id/eprint/13968

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