Arun Prakash, I (2020) A Study on Incidental Finding of Thyroid Malignancy in Benign Thyroid Disease. Masters thesis, Madras Medical College, Chennai.
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Abstract
BACKGROUND: To study the prevalence of thyroid carcinoma as an incidental finding in patients treated surgically for presumably benign thyroid disease. Thyroid disorders are most common endocrine disorders world wide. Most of the disorders surgery remains the corner stone in the management of thyroid disorders. My study mainly focuses on the diagnosis of malignancy in the post op HPE for various surgeries done eventhough preoperative evaluation shows the benign nature of disease OBJECTIVES OF THE STUDY: To study the prevalence of thyroid carcinoma as an incidental finding in patients treated surgically for presumably benign thyroid disease. MATERIALS AND METHODS: STUDY CENTRE: Institute of General surgery, Madras Medical College and Rajiv Gandhi Government General Hospital. DURATION OF STUDY: December 2017 TO January 2019. STUDY DESIGN: PROSPECTIVE AND RETROSPECTIVE(OBSERVATIONAL). SAMPLE SIZE: 102. INCLUSION CRITERIA: All patients with clinical,radiological and FNAC proven benign Thyroid Disease. EXCLUSION CRITERIA: Patients with radiological, cytological proven diagnosis of thyroid malignancy and pregnant women are excluded from this study. RESULTS: Prospective and Retrospective study on incidental finding of thyroid malignancy done at RGGGH Chennai from December 2017 to January 2019. A Total of 102 patients were observed . sex wise distribution shows female predominance.majority of solitary nodule found benign preop turned out to be malignant in post op HPE. Malignant suspicion in male goitre is high. Ratio of female to male in malignancy is 3:1 world wide our study also has similsr results. Incidence of malignancy in a sum of 102 patients is 4%. Papillary carcinoma being most common with 3% and follicular 1%. CONCLUSION: Thyroid disorders are most common disorder worldwide . In that thyroid neoplasms accounts about 1.7/100000 population with female to male ratio of about 3:1. Many advanced diagnostic modalities available. Surgery remains cornerstone in the management in most of thyroid malignancy. In our study around 102 patients are observed whose clinical presentation, radiological presentation, tissue diagnosis found to be benign pre operatively turned malignant on post operative histopathological examination with incidental finding of malignancy with percentage of 4 compared to global study in which the percentage is around 7.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 221711002 |
| Uncontrolled Keywords: | Incidental Finding, Malignancy, Papillary Carcinoma, Follicular Carcinoma, Goitre, Total Thyroidectomy, Hemithyroidectomy. |
| Subjects: | MEDICAL > General Surgery |
| Depositing User: | Subramani R |
| Date Deposited: | 09 Feb 2021 00:09 |
| Last Modified: | 09 Feb 2021 00:13 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/13926 |
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