Study of Distribution of Musculature Pattern and Cilia in Different Regions of the Fallopian Tube

Monisha, K (2020) Study of Distribution of Musculature Pattern and Cilia in Different Regions of the Fallopian Tube. Masters thesis, Thanjavur Medical College, Thanjavur.


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BACKGROUND: The fallopian tube which connects the ovary with the uterine cavity, which acts as a conduit for the passage of ovum and which facilitates the fertilization of sperm with the ovum is being bypassed now a days as a result of the advancement in artificial reproductive techniques. Still, there is no replacement for the oviduct in unassisted procreation. The four parts of the fallopian tube namely, intra uterine portion, isthmus, ampulla and fimbria need to be studied in detail to shed light on sub-fertility and ectopic pregnancy. AIM & OBJECTIVES: 1. To study the mucosal branching pattern, simple or complex in four parts of the fallopian tube namely, intra mural part, isthmus, ampulla and infundibulum. 2. To study the cilia distribution in various parts of the fallopian tube from tubo-uterine junction to fimbrial end of the fallopian tube. 3. To study the muscle architectural pattern in all four parts of the fallopian tube. 4. To apply the above findings with respect to age and to the clinical diagnosis of the patient for which they have proceeded with total abdominal hysterectomy and salpingo-oopherectomy. METHODOLOGY: The sections of the four intrinsic parts of the fallopian tube was grossed out from the specimens, obtained as a result of total abdominal hysterectomy with bilateral salpingo oopherectomy in patients of peri- menopausal age group. The sections were then preserved in 10% formalin. All the sections were stained with hematoxylin and eosin. Four of the slides were stained with Masson Trichrome, Von Gieson and Giemsa stains for elaborate understanding. The slides were then studied under 4x, 10x, 40x magnification using binocular light microscope (Magnus). Observations were noted and analyzed. RESULTS: The mucosal folding pattern was found to be simple in sections of tubo-uterine junction. In sections of isthmus, ampulla and fimbria, the folds became compound progressively. The cilia distribution was noted to be sparse in tubo uterine junction, less abundant in isthmus, abundant in ampulla and more abundant in fimbria. The musculature was found to be stratified as inner longitudinal and outer circular in sections of tubo uterine junction and isthmus, where as in ampulla, it consisted of a single layer of spiral musculature. In major fimbria, the muscle fibres were disposed of spirally with few fibres being longitudinally oriented. DISCUSSION: The fallopian tube which was thought to have a peristaltic action just like that of the intestine because of the stratified arrangement of musculature is disproved by recent studies and by the present study. Instead, the spirally oriented musculature in the ampulla was found cause stirring up of the contents of the fallopian tube thereby facilitating fertilization as well as development of human embryo. CONCLUSION: Though there are many procedures of assisted reproductive techniques that bypass the fallopian tube, its role in unassisted procreation is in-dispensable. Considering its importance in natural means of reproduction, the present study analyzed its various components under the categories of mucosal folds, cilia distribution and musculature of the four conventional parts of the fallopian tube. As quoted in previous studies, the mucosal folds increased in complexity towards the fimbrial end with no exceptions found. The cilia distribution becomes more abundantly distributed towards the fimbrial end. Musculature of the four parts of the fallopian tube is attributed to their specific functions. In the present study it could be found that the muscle fibres are stratified in the intramural and isthmic portions of the fallopian tube. Like most of the previously done studies, it was found that the circular layer was well developed owing to its sphincter like function. In the ampullary region the muscle fibres shows spiral orientation though controversy exists, the spiral orientation of muscle provides a physical basis for the mixing contractions of the ampulla. In the fimbrial end the major fimbria shows spirally oriented muscle fibres with intermingled longitudinal muscle fibres for aiding in the collection and transportation of ovum towards the uterine end of the tube.

Item Type: Thesis (Masters)
Additional Information: 201733152
Uncontrolled Keywords: fallopian tube, oviduct, cilia, musculature, light microscopy.
Subjects: MEDICAL > Anatomy
Depositing User: Subramani R
Date Deposited: 06 Feb 2021 03:45
Last Modified: 06 Feb 2021 03:45

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