Arul Raja, G (2020) A Comparative study on Efficacy of Microneedling Plus Subcision with and without 50% TCA Cross in Atrophic Acne Scars. Masters thesis, Chengalpattu Medical College and Hospital, Chengalpattu.
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Abstract
BACKGROUND: Post acne atrophic scars are difficult to treat and varied in their scar morphology. Several treatment modalities have been described which are classified into energy based devices and non energy based.The demand for less invasive but highly effective treatment for scars is growing. OBJECTIVE: This study is aimed at assessing the efficacy of microneedling plus subcision with and without 50% TCA CROSS in atrophic acne scars. The objective is to perform microneedling plus subcision with 50% TCA CROSS in the study participants of one group and microneedling plus subcision in participants of another group, thereby assessing efficacy of combination modalities and added benefit of 50% TCA CROSS in atrophic acne scars. MATERIALS AND METHODS: Sixty patients with Grade 2-4 atrophic acne scars(Goodman and Baron qualitative grading system) attending skin outpatient department of either sex, in age group 16-35 years were enrolled in the study and randomly divided into two groups. Thirty patients in group 1 were treated with Subcision plus 50% TCA CROSS at first visit, 6th and 12th week and Microneedling done at 3rd, 9th and 15th week. Similarly thirty patients in group 2 were treated with Subcision at first visit, 6th and 12th week and Microneedling done at 3rd , 9th and 15th week. Grading of acne scar photographs was done at baseline, at every sitting and 1 and 3 months after last procedure. Patient own evaluation of improvement was assessed. RESULTS: In both groups, all 12 patients with grade 2 improved to grade 1 (100% improvement). 14 patients in group 1 with grade 3 scars, 5 (35.7%) patients improved to grade 1 and 9 (64.3%) patients to grade 2. Out of 14 patients in group 2, 4 (30.7%) patients improved to grade 1 and 9 (69.3%) patients improved to grade 2. In patients with grade 4 scars, improvement to grade 2 is seen in 80% (8) and 75% (6) of patients in group 1 and 2 respectively. 2 patients in each groups with grade 4 scar show only one grade improvement. Eventhough there was significant improvement in scar grade in both groups before and after treatment, there was no statistically significant difference in scar grade improvement between two groups (P value > 0.005). CONCLUSION: The combination of microneedling and subcision with and without 50% TCA CROSS showed that combination therapy is effective in treating atrophic acne scars rather than unimodal therapy. But no stastical different seen between improvement in both groups,thus questioned the efficacy of 50% TCA CROSS in atrophic acne scars.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 201730151 |
| Uncontrolled Keywords: | Atrophic acne scars, energy based, non-energy based, subcision, microneedling, 50% TCA CROSS. |
| Subjects: | MEDICAL > Dermatology Venereology and Leprosy |
| Depositing User: | Subramani R |
| Date Deposited: | 05 Feb 2021 02:41 |
| Last Modified: | 05 Feb 2021 02:41 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/13875 |
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