Study the Prevalence of Renal Function Defects in COPD Patients using Creatinine Clearance and Urine Protein Analysis

Vignesshkanth, R (2020) Study the Prevalence of Renal Function Defects in COPD Patients using Creatinine Clearance and Urine Protein Analysis. Masters thesis, Kilpauk Medical College, Chennai.

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Abstract

INTRODUCTION: COPD a major concern of the developing world has been associated with a number of comorbidities. Hypoxia and Renin angiotensin activation induced renal injury is an unexplored area of concern. AIM AND OBJECTIVE: To estimate the level of renal function defects in COPD patients using creatine clearance by cockcroft gault equation and urine protein analysis. MATERIALS AND METHODS: Over a period of 1 year, a cross sectional study done among COPD patients by calculating creatinine clearance using cockcroft gault equation. RFT values were calculted among newly diagnosed and previously diagnosed COPD patients as per GOLD guidelines. From RFT, Creatinine Clearance is calculated using cockcroft gault equation. RESULTS: Creatinine clearance was calculated among 146 patients and found to be significantly reduced with a prevalence of 81%, overt renal failure of 7%, concealed renal failure of 34.9%. Risk of renal failure using different range of creatinine clearance values has been tabulated. LIMITATION: Normal group is not compared. Includes Diabetic and hypertensive sub population. CONCLUSION: Renal function is impaired in COPD patients.

Item Type: Thesis (Masters)
Additional Information: 201727053
Uncontrolled Keywords: Prevalence of Renal Function Defects, COPD Patients, Creatinine Clearance, Urine Protein Analysis.
Subjects: MEDICAL > Tuberculosis and Respiratory Medicine
Depositing User: Subramani R
Date Deposited: 04 Feb 2021 16:22
Last Modified: 04 Feb 2021 16:22
URI: http://repository-tnmgrmu.ac.in/id/eprint/13811

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