A Prospective study on Inspiratory Muscle Training using Different Techniques to Improve Pulmonary Function and Quality Of Life in COPD Patients in a Tertiary Care Centre

Sivashanmugam, M (2020) A Prospective study on Inspiratory Muscle Training using Different Techniques to Improve Pulmonary Function and Quality Of Life in COPD Patients in a Tertiary Care Centre. Masters thesis, Stanley Medical College, Chennai.


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INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a common preventable and treatable chronic respiratory disease. According to global burden do disease study 2010, COPD is a leading cause of morbidity and mortality worldwide. Respiratory and peripheral muscle dysfunction are the common extrapulmonary manifestations, which are often present in patients with COPD. The pathogenesis for such respiratory and peripheral muscle dysfunction is multifactorial which includes inflammation, oxidative stress, smoking, aging and other associated comorbidities. This muscular dysfunction results in hypoxemia, dyspnoea and decreased exercise tolerance, which impact negatively on health-related quality of life. Pulmonary rehabilitation including exercise training, education, nutritional intervention and psychosocial support is a standard care for patients with COPD to counteract disease manifestations. AIM AND OBJECTIVES: The aim of the study is to investigate the role of Inspiratory Muscle Training (IMT) and Peripheral Muscle Training as a adjuvant therapy in improving exercise capacity, Quality Of Life (QOL) and pulmonary function among the COPD patients. MATERIALS AND METHODS: 100 COPD patients were enrolled in the study, they were randomised by simple randomisation into 2 groups : inspiratory muscle training group (using THRESHOLD ®, inspiratory muscle trainer device) and peripheral muscle training group (using THERABAND ® elastic resistance loop). Among them 43 subjects in inspiratory muscle training group and 39 subjects in peripheral muscle training arm completed the training program. Each training session lasts for 15-20 mins for 6 days a week for 3 weeks duration. The following parameters are measured at the baseline and after the completion of 3 weeks training program, the results were tabulated and analysed using standard statistical software: 1) mMRC dyspnoea score, 2) COPD Assessment Test (CAT) score - As a measure of Quality of life, 3) Body Mass Index (BMI), 4) 6 Minute Walking Distance (6 MWD), 5) Oxygen saturation (SpO2) - As a measure of exercise capacity, 6) Forced Expiratory Volume in one second (FEV1) – As a measure of lung function. RESULTS: Statistically significant improvement in mMRC dyspnoea grading, CAT score and 6MWD were seen in both inspiratory and peripheral muscle training groups. (P = 0.013, 0.038, 0.055 and P = 0.019, 0.044, 0.048) respectively, whereas no significant improvement were seen in SpO2%, BMI and FEV1% values in both the training groups. CONCLUSION: Thus a 3 week training program of inspiratory and peripheral muscle training shown improvement in quality of life and exercise capacity, whereas no significant improvement is seen in lung function in the patients with moderate to severe COPD.

Item Type: Thesis (Masters)
Additional Information: 201727056
Uncontrolled Keywords: COPD, Inspiratory Muscle Training, Peripheral Muscle Training, Pulmonary Rehabilitation, Quality of life, exercise capacity, lung function.
Subjects: MEDICAL > Tuberculosis and Respiratory Medicine
Depositing User: Subramani R
Date Deposited: 04 Feb 2021 16:14
Last Modified: 04 Feb 2021 16:14
URI: http://repository-tnmgrmu.ac.in/id/eprint/13809

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