Comparison between Medical Thoracoscopic Pleural Biopsy and Pleural Brush Cytology in Undiagnosed Exudative Pleural Effusions: A Prospective study

Mathiyalagan, M (2020) Comparison between Medical Thoracoscopic Pleural Biopsy and Pleural Brush Cytology in Undiagnosed Exudative Pleural Effusions: A Prospective study. Masters thesis, Stanley Medical College, Chennai.

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Abstract

INTRODUCTION: The accurate diagnosis of pleural effusion remains a challenging clinical problem. Medical thoracoscopy has an established role in diagnosis of the undiagnosed exudative pleural effusion. Medical thoracoscopy, when combined with pleural brush cytology, may reduce time to diagnose the undiagnosed pleural effusion and is less complicate when compared to Pleural Biopsy. AIM OF THE STUDY: 1. To compare the yield of Medical Thoracoscopic Pleural biopsy and Thoracoscopic Pleural brush cytology in undiagnosed exudative pleural effusions. 2. To minimize the Thoracoscopy Pleural biopsy complication by doing pleural brush cytology for undiagnosed exudative pleural effusion. STUDY DESIGN: Prospective study. PATIENTS AND METHODS: The study was done between December 2018 and June 2019 in all the patients of undiagnosed exudative pleural effusions who were taken for thoracoscopy. Both medical thoracoscopic pleural biopsy and pleural brush cytology were obtained for all the patients. RESULTS: Sample size 40. The mean age was 54 years. Thoracoscopy morphology nodule was the most common finding on thoracoscopic examination. thoracoscopic pleural biopsy was found to be positive in 34 patients out of 40.whereas thoracoscopic pleural brush cytology was found to be positive in 32 patients out of 40.in thoracoscopic pleural biopsy out of 34 positive cases, 20 were observed having malignancy whereas in case of thoracoscopic pleural brush cytology out of 32 positive cases 19 were diagnosed having malignancy.among the 40 cases 22 cases had minor complication during thoracoscopy procedure. CONCLUSION: Thoracoscopic pleural brushing could be done easily and safely and allows obtaining pleural cellular material in areas dangerous to take biopsy specimens. It could augment the diagnostic yield of a medical thoracoscopy in undiagnosed exudative pleural effusion cases.

Item Type: Thesis (Masters)
Additional Information: 201727053
Uncontrolled Keywords: Medical Thoracoscopy Pleural Biopsy, Medical Thoracoscopy Pleural Brush, Undiagnosed Pleural Exudative Pleural Effusion, Malignant Pleural Effusion.
Subjects: MEDICAL > Tuberculosis and Respiratory Medicine
Depositing User: Subramani R
Date Deposited: 04 Feb 2021 16:04
Last Modified: 04 Feb 2021 16:04
URI: http://repository-tnmgrmu.ac.in/id/eprint/13806

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