Gireesh, G K (2013) Clinical and Angiographic profile of patients with angina and normal epicardial coronaries : A study using Clinical, Biochemical, Electrocardiographic, Echocardiographic and Angiographic Variables. Masters thesis, Christian Medical College, Vellore.
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Abstract
BACKGROUND : Angina with normal epicardial coronaries occurs in upto 20% of patients who underwent coronary angiogram for angina. Coronary slow flow comprises a separate group among this population designed Syndrome Y and accounts for upto 7% of patients undergoing CAG for angina. Coronary slow flow is characterized by the delayed passage of contrast injected into the epicardial coronaries. Conventionally, coronary slow flow is determined by the coronary filling time. We tried to determine whether coronary emptying time is a significant predictor of coronary slow flow METHODS : We selected consecutive patients, who underwent angiogram for angina and found to have normal epicardial coronaries, randomly between the study period November 2011 and November 2012. We assessed the coronary filling and emptying times at prespecified standard vascular landmarks on the basis of TIMI frame counts RESULTS : We analysed the angiograms of 37 patients. 27 patients had LAD slow flow and 17 patients had RCA slow flow (10 had normal flow in LAD and 12 had normal flow in RCA). 8 had non dominant small RCA and was excluded from the study. We observed positive correlation of coronary filling times and emptying times, both in LAD and RCA, in slow flow patients unlike those with normal flow. We found the filling times and emptying times are significantly prolonged in slow flow patients (p value <0.05) in LAD and RCA. Capillary and venous transit time is prolonged in both LAD and RCA slow flow groups, but was significantly prolonged in RCA slow flow patients. (Pvalue <0.05, LAD slow flow group, P value 0.43). We observed slow flow significantly more in male population and significantly associated with high LDL/HDL ratios and high triglycerides. CONCLUSION : Coronary emptying time is an independent and significant predictor of Coronary Slow Flow Phenomenon.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | angina ; normal epicardial coronaries ; Clinical and Angiographic profile. |
| Subjects: | MEDICAL > Cardiology |
| Depositing User: | Kambaraman B |
| Date Deposited: | 10 Jul 2017 23:15 |
| Last Modified: | 10 Jul 2017 23:15 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/1359 |
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