A Comparative study of Pure Tone Audiometry and Brain-Stem Evoked Response among Type 2 Diabetic and Non-Diabetic Individuals

Jothilakshmi, M V (2020) A Comparative study of Pure Tone Audiometry and Brain-Stem Evoked Response among Type 2 Diabetic and Non-Diabetic Individuals. Masters thesis, Karpaga Vinayaga Institute of Medical Sciences and Research Centre, Kanchipuram.


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INTRODUCTION: Diabetes mellitus causes pathophysiological changes at multiple organs. Brainstem Evoked Response Auditory (BERA) represents a non-invasive tool to detect diabetes related sensorineural hearing loss. AIMS AND OBJECTIVE: To evaluate the association between diabetes and hearing loss. To identify type of hearing loss in type-2 diabetic patient by using pure tone audiometry. To localize the level of lesion in auditory pathway in type-2 diabetic patients by using brain-stem evoked response. MATERIALS AND METHODS: The study comprises two groups, (i) Diabetic group (n=50), (ii) Control group (n=50). The controls were matched for age and sex with the study group. BERA was done for all these patients after detailed clinical examination and relevant blood investigations. RESULTS: There was statistically significant (P value <0.05)latency differences found in wave III, IV, V and interpeak latencies III-V and I-V between control and study groups. The number of moderate hearing loss was increased from 1(5%) to 11(57.89%) when the duration DM increased from 1 to 3 years to 4 to 6 years. CONCLUSION: The wave I latency was found non significant which suggests that the pathway from 8th nerve to cochlear nucleus is not affected in diabetic patients. The delay in latencies III and V and interpeak latencies I-III, III-V and I-V in diabetic patients compared to the controls suggests brainstem and midbrain involvement. So the study suggests that BERA helps in early detection of central neuronal axis involvement in type-2 diabetes mellitus.

Item Type: Thesis (Masters)
Additional Information: 201715601
Uncontrolled Keywords: Brainstem evoked response audiometry, Type-2 diabetes mellitus, Sensorineural hearing loss.
Subjects: MEDICAL > Physiology
Depositing User: Subramani R
Date Deposited: 30 Jan 2021 17:27
Last Modified: 01 Mar 2021 02:08
URI: http://repository-tnmgrmu.ac.in/id/eprint/13509

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