A Study of Peripheral Vascular Disease in Individuals with Hypertension

Poihai, A (2020) A Study of Peripheral Vascular Disease in Individuals with Hypertension. Masters thesis, Madurai Medical College, Madurai.

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Abstract

BACKGROUND: Hypertension accounts for about 18% of deaths globally. Hypertension is a major risk factor for Peripheral Vascular Disease which is asymptomatic in most individuals. ABPI is a simple, less expensive, non invasive and an effective indicator for diagnosing Peripheral Vascular Disease even in asymptomatic individuals. AIM AND OBJECTIVE: To study the antidepressant effect of aqueous extract of fruits of Embilica offilinais in adult male albino mice. METHODS: 100 postmenopausal female hypertensive patients without any symptoms of Peripheral Vascular Disease and 100 age and BMI matched normotensive females were included in the study. Ankle Brachial Pressure Index (ABPI) was measured using a Hand held Vascular Doppler. The ABPI of both the groups were compared and the risk of peripheral vascular disease in postmenopausal female hypertensive patients without any symptoms of Peripheral Vascular Disease was predicted. RESULTS: Postmenopausal female hypertensive patients had ABPI (0.94 ) lesser than the normotensive patients (1.01) and the p value was significant(0.000005) i.e., they have higher risk of Peripheral vascular disease. CONCLUSION: ABPI is a safe, sensitive, reliable and a non invasive test used to diagnose Peripheral Arterial Disease. So this test may be included in the protocol for screening Peripheral Vascular Disease in Hypertensive patients so as to diagnose future atherosclerotic accidents earlier.

Item Type: Thesis (Masters)
Additional Information: 201715101
Uncontrolled Keywords: Peripheral Vascular Disease, Individuals, Hypertension.
Subjects: MEDICAL > Physiology
Depositing User: Subramani R
Date Deposited: 30 Jan 2021 16:49
Last Modified: 01 Mar 2021 03:21
URI: http://repository-tnmgrmu.ac.in/id/eprint/13488

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