Arul Varuni B, (2020) Study of Haematological and Coagulation Profile in Snake Bite Patients in GMKMC, Salem. Masters thesis, Government Mohan Kumaramangalam Medical College, Salem.
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Abstract
BACKGROUND: Snake bite is a common medical emergency and occupational hazards in most parts of India. Coagulopathy is a common manifestation in cases of snake bite and its abnormality can be detected by blood coagulation tests. AIM OF THE STUDY: To study the most common species of snake, clinical manifestations, coagulation abnormalities before and after the admiration of Anti-Snake venom. MATERIALS AND METHODS: 70 patients who experienced snake bite were enrolled in the study. Blood samples collected and analysed for coagulation abnormalities. RESULTS: In the present study, PT was recorded as NCD in 2.9%, prolonged in 71.4% and normal in 25.7% of patients before administration of ASV. After the administration ASV, No cases had NCD, 22.9% had prolonged PT and 77.1% normal PT. APTT was recorded as NCD in 4.3%, prolonged in94.3% and normal in 1.4% of patients before administration of ASV. After the administration ASV, No cases had NCD, 95.7% had prolonged APTT and 4.3% normal APTT. TT was recorded as NCD in 8.6%, prolonged in 42.9% and normal in 48.6% of patients before administration of ASV. After the administration ASV, No cases had NCD, 7.1% had prolonged TT and 92.9% normal TT. Fibrinogen was recorded as NCD in 27.1%, less than 150 mg/dl in 1.4% and normal fibrinogen level in 71.4% of patients before administration of ASV. After the administration ASV, No cases had NCD, 7.1% had Fibrinogen less than 150 mg/dl and 85.7% normal Fibrinogen levels. CONCLUSION: Coagulation markers (PT, APTT, TT, Fibrinogen) should be considered as first line of investigation before and after the administration of ASV to assess the severity of the venom.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 201713751 |
| Uncontrolled Keywords: | Snake bite, coagulation markers, PT, APTT, TT, Fibrinogen, Anti-Snake Venom. |
| Subjects: | MEDICAL > Pathology |
| Depositing User: | Subramani R |
| Date Deposited: | 29 Jan 2021 17:30 |
| Last Modified: | 29 Jan 2021 17:30 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/13423 |
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